Zoladex and mood swings

[Janaphi32]

Hello everyone! Im 32 on hormonal therapy with tamoxifen and zoladex and about one week before my shot i have anxiety depression aches in my knees crying all the time and most of the time i dont know why. I don't want to go out and see friends and have negative and confused thoughts that float into my head. It is scaring me that I feel so bad mentally wise. I've been having zoladex injections for the last 1 year and wonder if it is because of this? Anyone else experiencing the same side effects? Thanks!

[Louisejr]

Hi there

I could be writing what you have put. I'm a week away from my next injection and feeling all over the place. I've actually just come up to bed to have 5 mins on my own as I'm feeling very low and emotional. Literally every thing hurts, even my fingers and thumbs.

It definitely ebbs and flows in between injections. I am only 6 months in and was hoping things would improve but it is definitely difficult. I am on Letrozole too - and was wondering which was making me feel worse but I guess as both have similar side effects it is probably both.

I have started bathing with Magnesium Flakes and it does seem to be helping. I also drink plenty of water which also seems to help too, when I feel like I am right now.

I don't know about you, but I always feel better knowing that someone else is experiencing the same things and means I'm not nuts or imagining it all.

Sending you hugs 🤗

Louise xx

[Janaphi32 in reply to Louisejr]

It definitely helps knowing that someone else is experiencing this symptoms and that im not going nuts i tried epsom salt i cant say it helps much. I think that is very low estrogen that has to do with this and nothing much can be made. Are you on hormonal therapy for breast cancer too? Thanks a lot louise!! Xxxx

[Janaphi32 in reply to Janaphi32]

What is letrozole for?

[Louisejr in reply to Janaphi32]

Sorry missed this - letrozole is an alternative to Tamoxifen it is an inhibitor xx

[Janaphi32 in reply to Louisejr]

Im going for a walk now. Hope it will make me feel better take care xxx

[Louisejr in reply to Janaphi32]

My other half is out today - so going to have a pamper day 👍enjoy your walk xx

[Janaphi32 in reply to Louisejr]

Thanks u 2!! Xxx

[Louisejr in reply to Janaphi32]

Hi, yes I am on Letrozole. I had a lumpectomy and sentinel node removal last October, followed by radiotherapy. I think I thought that after the op and RT I would be back to normal but definitely underestimated the side effects of the drugs. Most of the time I feel like I am in a bubble, and it is difficult to explain to people who have not gone through this how you actually feel. Having no hormones does affect you mentally.

My cousin who is 2 years down this road from me suggested Magnesium, and I def can feel a difference.

I don't know about you but in some way knowing that you are not imagining all of this and that these side effects are real goes a little way to feeling better about it all.

Take care

Louise 😘

[Janaphi32 in reply to Louisejr]

I know and feel its all about the hormones thats why im saying we cant do much about it. I feel like im a different person for some days. And like these days when i think about it a lot it gets me very low. Our mind confuses us easily. i also went to a homeopathy doctor and discovered im low in vitamin d propably from chemotherapy so im taking also vitamin d and cod liver oil to cleanse it. Im on antidepressants too for 4 months but i think its not needed. Its all games of the mind prior to my ' period' which i dont have

[Janaphi32 in reply to Louisejr]

Btw magnesium does the same thing with epsom salt. It indeed relaxes u a bit Hugs to u!

[Louisejr in reply to Janaphi32]

Will give them a try.

Hugs to you too 🤗😘

[Debs1962]

Sound s like Louise knows what you are going through which I think really helps to not feel alone, what injections are you on? And what are they for?

I hope you can get some relief from the side effects, and maybe try the suggestions from Louise xx

[Louisejr in reply to Debs1962]

Hi Debs

The Zoladex basically puts your ovaries to sleep to stop you producing oestrogen if you are pre menopause. I am 52 but when they did blood tests they said I was not near menopause as my oestrogen levels were very high. I think it is more usually given to ladies that are much younger than me and does not affect their fertility. As I am older and my child bearing days long gone I am going to ask about ovary removal as I am struggling with the side effects.

Louise 😘

[Debs1962 in reply to Louisejr]

Oh I see now, I was 52 when diagnosed now 54 but was already in the menopause so just on letrozole, sounds like you may benefit from op to remove ovaries xx

[Janaphi32 in reply to Debs1962]

Hi debs. The zoladex injection is for stopping my period and lowering the estrogen as a preventive measure of cancer to reoccur. It definitely helps to not feel alone. Thanks! Xxx

[Debs1962]

That is the great thing about this site, you are never alone xx

[Artemis-angel]

I too take zoladex and get days when I feel down and emotional which is not like me at all. I find it's either just before my next injection or around the time of my next monthly cycle.

[Janaphi32 in reply to Artemis-angel]

How old are you? Sending u hugs! We are gonna get through this!

[Artemis-angel in reply to Janaphi32]

52 I've been taken zoladex about 6 years hopefully coming off it soon

[Louisejr in reply to Artemis-angel]

I'm supposed to have it for 2 years - counting down on Thursday it will be six so 18 to go 🙄xx

[Janaphi32 in reply to Louisejr]

Im on zoladex for 5 years. We ll see how it goes :/

[Janaphi32 in reply to Artemis-angel]

U ve been through a lot. Hope your problems end soon xxx

[Louisejr in reply to Janaphi32]

Thank you - both my Mum and Cousin have had BC and are both survivors and as they keep telling me you've just got to get through it 😘

[Lana0322]

I am 29 and I had breast cancer 2 years ago and I went throw it all I had a bilateral mastectomy the did hard core chemo now I'm on zoladex and letrozole for hormone therapy I'm glad I found this page by googling lol I haven't had any side effects and November will be 2 years I've been on this medicine but just had my shot Thurs and probably sat I started getting knee pain sharp pains threw my left knee so is that from the shot? I've never had it happen before so I don't know should I ask my doctor?

[janaphi in reply to Lana0322]

i have the same thing too! and i kinda feel my knees hurt and makes me wonder if it has something to do with osteoporosis. im 32 btw

[Lana0322 in reply to janaphi]

I'm not sure my doctor said I was to young to have to worry about it but I don't know ill have to say something to her it just started