Hello everyone! Im 32 on hormonal therapy with tamoxifen and zoladex and about one week before my shot i have anxiety depression aches in my knees crying all the time and most of the time i dont know why. I don't want to go out and see friends and have negative and confused thoughts that float into my head. It is scaring me that I feel so bad mentally wise. I've been having zoladex injections for the last 1 year and wonder if it is because of this? Anyone else experiencing the same side effects? Thanks!