indapamide / Tinnitus

[Ropa511]

Hello Peeps,

I recently went up from 1.25mg indapamide daily (half 2.5mg pill esch day) to 1.5mg indapamide extended release.

Fairly quickly I noticed a low volume pulsating humming sound at home, particularly in the evenings that sounded a bit like there was an engine running. I even asked neighbours, and put something out on my community facebook page to see if they could hear the same?!

Gradually I realised that I was suffering from a form of tinnitus, and started getting some anxiety, palpitations, aches and pains and felt a bit spacey also.

I have now reduced back to 1.25mg and low and behold suddenly feel much better.

Has anybody out there had similar experiences with indapamide???

Interesting that a relatively small increase of dosage should cause such an increase in side effects…

[springcross]

Hi Ropa511. Yes, I did a couple of years ago. I already had very mild tinnitus but Indapamide made it so much worse so I had to stop it.

[Madlegs1]

That's gas!

I've noticed my tinnitus getting worse over last while.

I was wondering if it was the Amlodipine, and was going to research it!

Just an insistent ticking noise, but getting worse.

Just gone on Google. This is first thing came up!

"

Calcium channel blockers are a common potential cause of tinnitus. Examples include amlodipine, diltiazem, nicardipine, and nifedipine. Certain beta blockers. “Some instances of beta blockers have been associated with tinnitus or other means of ototoxicity, such as bisoprolol and metoprolol,” Heche says.10 Apr 2023. "

[springcross in reply to Madlegs1]

Yes, so true - I've been on Amlodipine for four years now and I get those little clicks too, they last a short while and then go but the tinnitus is getting worse as time goes on!

[Jourdanie007]

Glad you said that exactly the same has happened to me and I’ve taken it further been to an ENT specialist although he poo pooed the link. The Indapamide has definitely brought my blood pressure down, I have a telephone interview with him coming up so I will mention it again how weird is that

[Sleepyholllow]

hello Ropa511

Funny you should mention that!! I take Lercanidipine (which is a calcium channel blocker) and recently had dose increased from 10mg to 20mg, and am really struggling with tinnitus!

Can someone please tell me what bp meds cause least side effects, I am seriously fed up of feeling like half a person on these drugs ☹️☹️

[springcross in reply to Sleepyholllow]

If only we could tell you, we'd be taking whatever ourselves. Some people are on the same drugs for years and never get a problem but others are not so fortunate.

[Sleepyholllow in reply to springcross]

Oh i know! It would be like winning the lotto to find one!!

[springcross in reply to Sleepyholllow]

Absolutely agree!

[Madlegs1 in reply to Sleepyholllow]

Angiotensin II receptor blockers (ARBs). When taken without other blood pressure medications, ARBs like candesartan, olmesartan and telmisartan are not linked to tinnitus.Certain beta blockers. While some beta-blockers are associated with tinnitus, like those listed above, others are not.

5 May 2023

[Sleepyholllow in reply to Madlegs1]

Thanks for that, I have a gp appt soon I will mention that.