Hi husband is taking ramipril, indepamide and bisoprolol for a good few months now and feels pretty rubbish most of the time constantly tired we've been doing BP readings all week and he's averaging 130/90 again. His levels had come down a fair bit when first taking all 3,is it normal for them to suddenly be less effective and how did people fix this, surely he can't just keep taking more and more pills forever.
Any ideas appreciated - he is only 40 and no specific cause found for high BP