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Stopping clopidogrel

Comfycousin1 profile image
101 Replies

I had a heart attack the week before christmas 2023 and had a stent fitted.I spoke to my GP surgery pharmacist last week and I'm told I'm due to stop my blood thinner (clopidogrel)on 22nd Dec but I'm nervous about stopping them. Especially before/ over Christmas. I'm a bit anxious about increased risk.

I will still be on disperable aspirin but am wondering if I should gradually taper off the clopidogrel or have others stopped completely?

What experiences have others had please?

C

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Comfycousin1
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101 Replies
Wonky_heart profile image
Wonky_heart

I was on edoxaban and clopidogrel after my stent and told to stop the clopidogrel after 12 months. I checked with the cardiologist when the 12 months was up and she said yes, to just stop, which I did. That was three months ago and I've had no problems.

Comfycousin1 profile image
Comfycousin1 in reply toWonky_heart

Thank you

devonian186 profile image
devonian186 in reply toComfycousin1

When applying for a renewed prescription I reminded the inhouse pharmacist that this med was supposed to cease after 12 months. I was glad to reduce the number of meds. It was stopped, I stopped taking it and had no problems. I still take low dose aspirin.

Big advantage is that the bruising that could start as soon as I looked at a hard surface reduced considerably.

bikerider00 profile image
bikerider00 in reply todevonian186

Re. bruising. Oh Good! I should be due to stop mine in late Jan (+12 months from MI). I am really hoping that even while staying on low dose aspirin my propensity to look like an overripe banana will disappear afterwards. I'm fairly active, and can easily find myself with bruises I didn't even know to expect, especially after a bit of MTB riding.

Karicrow profile image
Karicrow in reply toWonky_heart

I was on Clopidogrel for quite a while after I had a stent and then it was stopped but I am still taking aspirin as a blood thinner 3 years after and I have gradually been taken off other medication as well, the last being Bisoprorol. I am still on Elantan LA25 and also take 20mg Pravastatin (which I halve each night as I'm not too keen on taking Statins!). At the moment all seems well thank goodness! I'm sure you don't need to worry.

Comfycousin1 profile image
Comfycousin1 in reply toKaricrow

Thank you

Lowerfield_no_more profile image
Lowerfield_no_more

I believe it is common practice to prescribe two anti platelets following a heart attack, which is then is reduced to one after 12 months. I was also on clopidogrel and low dose aspirin after my NSTEMI ,and after 12 months I stopped the clopidogrel and that left me on low dose aspirin for life. I do not recall any problems about stopping clopidogrel 'overnight' and I was pleased that I could drop one of the meds I needed to take. No need to get concerned is my advice.

Comfycousin1 profile image
Comfycousin1 in reply toLowerfield_no_more

Thank you. I'm on aspirin too and yes, I'm staying on that. I guess I'm just a bit anxious dropping something that is controlling my risk.

Isobel1 profile image
Isobel1 in reply toComfycousin1

If you're not sure, could you make an appointment to speak to your GP ?

Comfycousin1 profile image
Comfycousin1 in reply toIsobel1

It's not that I'm not sure. Just a bit nervous.

Isobel1 profile image
Isobel1 in reply toComfycousin1

I can understand that. Is it because it's stopping just before Christmas, or are you just nervous in general about stopping the Clopidogrel?

Comfycousin1 profile image
Comfycousin1 in reply toIsobel1

I think it's because it's just before Christmas and my diet might be slightly worse... or the medical support might be reduced eg GP closed.I know it's the statins that help protect against cholesterol build up and that 999 never closes. It's just my brain.

Isobel1 profile image
Isobel1 in reply toComfycousin1

Perhaps you could ask to just continue it until January if you are worried.

Comfycousin1 profile image
Comfycousin1 in reply toIsobel1

I've asked the GP. Awaiting a response. Thanks for your support 😀

Isobel1 profile image
Isobel1 in reply toComfycousin1

🙂❤️👍

Comfycousin1 profile image
Comfycousin1 in reply toIsobel1

I've emailed the cardiologist and he's said it's fine to stop.

pasigal profile image
pasigal in reply toLowerfield_no_more

Interestingly, I had an annual checkup with my kidney specialist (other issue) and she noticed that I was no longer on ramipril and asked me why. I told her that my cardiologist said it was only for a year after my last stent/HA. She seemed a little confused but I'd always heard that it was standard practice...I'm still on plavix as a blood thinner.

Comfycousin1 profile image
Comfycousin1 in reply topasigal

I was definitely told it was one of the blood thinners I needed to stop after a year. The GP has it on my notes. I'm still on aspirin but like many here the clopidogrel stops after a year.

Ageingfast profile image
Ageingfast

I stopped the aspirin at an early stage but keep taking clopidogrel.

When I needed a different op/ the dentist then I just stopped clopi. Then restarted after the op etc.

I love clopidogrel because , for me, it prevents migraine.

But of course you should keep within your medics recommendations.

Sooty

Comfycousin1 profile image
Comfycousin1 in reply toAgeingfast

I think that there was minimal damage at the time and I was only put on it to protect the stent. The cardiologist said at the time that I'd only need to take it for a year but that I'd be on everything else (including aspirin) for life. I guess I'm just a bit nervous about stopping it. Knowing that it's been managing the risk up until now, I mean.

DWizza profile image
DWizza in reply toComfycousin1

I had nstemi and quadruple bypass July 2023, was in clopidogrel for 12 months, stopped no problems. One less tablet to worry about . On aspirin, pantaprazole, bisoprolol and Rosuvastatin. 👍🏻

Comfycousin1 profile image
Comfycousin1 in reply toDWizza

Thank you

Happyrosie profile image
Happyrosie

the risk lessens over time, I’m given to understand, assuming that you maintain a good lifestyle and diet. You have healed.

Clop is sometimes résumes if something else happens. For example, in my husband’s case he had to be re-stented . In this instance it was decided he would have to restart Clop and be on it for life. I had a look at the NICE guidance for this scenario, and it implied it was up to the discretion, knowledge and training of the cardiologist

Comfycousin1 profile image
Comfycousin1 in reply toHappyrosie

Thank you. The cardiologist said at the time that I'd only need to take it for a year but that I'd be on everything else (including aspirin) for life. I guess I'm just a bit nervous about stopping it. Knowing that it's been managing the risk up until now, I mean.

Happyrosie profile image
Happyrosie in reply toComfycousin1

and the risk has reduced so you shouldn’t need it.

Mentdent profile image
Mentdent

I just stopped it. That was three years ago. Nothing happened.

Comfycousin1 profile image
Comfycousin1 in reply toMentdent

Thank you

Whatjusthapened profile image
Whatjusthapened

Hi

I was on both as well. Only they took me off aspirin and kept me on the clopidogrel. Im sure your GP will allow you to take it for another month for your mental wellbeing.

Comfycousin1 profile image
Comfycousin1 in reply toWhatjusthapened

I'll ask them. Thank you

Charl70 profile image
Charl70

Hi I had quadruple heart bypass in Sept 22 and stopped clopidogrel a year later with no side effects ,I also stopped amloadpine after 8 months with no side effects ,I'm still currently on bisoprolol 2,5mg asprin 75mg,and avrostatin 80mg

All the best

Comfycousin1 profile image
Comfycousin1 in reply toCharl70

Thank you

As others have said, your risk has reduced after a year, while the possible risk of abnormal bleeding continues on the clopidogrel. It's a matter of balancing risks, and the best advice after stenting is to cease clopidogrel after a year. We all understand your hesitation, but the doctor's advice is optimal. Best wishes

Comfycousin1 profile image
Comfycousin1 in reply to

Thank you

Joliv61 profile image
Joliv61

I had the same feelings after my nstemi in nov 2019, annd 3 stents fitted. After a year just stopped the clopidogrel and leaving me on the 75mg Aspirin seemed odd that I wasn’t weaned off it. But no ill effects from just stopping this.

Comfycousin1 profile image
Comfycousin1 in reply toJoliv61

Thank you

Stent2024 profile image
Stent2024

like you . I am due to stop mine in January, but nervous as I have a long haul flight to Jamaica in Feb . But was told ok to go with the aspirin after my stents been in a year . Which will be in January. Good luck

Comfycousin1 profile image
Comfycousin1 in reply toStent2024

It's just nerves. I'm glad I'm not the only one feeling weird about it. Good luck with your continued recovery and enjoy Jamaica.

Stent2024 profile image
Stent2024 in reply toComfycousin1

Thank you

Oaks6 profile image
Oaks6

I’ve been on Clopidogrel twice 5 years apart. Each was for a year and i was told to stop completely in each case. Like you I was nervous each time.

I had 3 stents in the first case. I had nightmares both times when taking Clopidogrel ( which I was told it was unlikely to have caused them ) it’s odd the nightmares stopped when I stopped taking it.

I’m on aspirin and Bisoprolol for life now.

Comfycousin1 profile image
Comfycousin1 in reply toOaks6

Thank you.

Blackknight57 profile image
Blackknight57

i was on an alternative. They stopped it after 18 months.

Was on aspirin until they found a clot. Now on warfarin.

Just make sure you have regular checkups

PilgrimsProgress profile image
PilgrimsProgress

There is no evidence of additional benefit if dual therapy is continued for greater than a year.. There is no evidence that "tapering off" confers any benefit ...

Comfycousin1 profile image
Comfycousin1 in reply toPilgrimsProgress

Thank you

Plastow48 profile image
Plastow48

I stopped immediately once I was put on Apixaban. I didn't have any problems.

Bahamasgirl profile image
Bahamasgirl

When people receive stents (the tiny metal mesh tubes that help open narrowed arteries), doctors routinely prescribe aspirin along with another medication that prevents clots. These drugs include clopidogrel (Plavix), prasugrel (Effient), and ticagrelor (Brilinta). Like aspirin, they prevent blood components called platelets from sticking together and forming clots. Clots that form inside the stent — known as stent thrombosis — can lead to a heart attack.

The combination of aspirin and one of those stronger antiplatelet drugs is known as dual antiplatelet therapy (DAPT). The question of how long people should stay on DAPT has been a matter of debate for years. Current guidelines suggest at least one year in people who needed an emergency stent placement and at least six months after a nonemergency stent procedure. But doctors may adjust this timeline based on an individual's specific situation. For example, people who receive a stent after a heart attack or acute coronary syndrome (a sudden loss of blood flow to the heart) may benefit from staying on the drugs for an additional period beyond the first year, potentially indefinitely.

JennyRx profile image
JennyRx

clopidogrel is to stop your stent getting clogged up post insertion. 12 months is regarded as a safe cut off to ensure that. Aspirin is the ongoing one to reduce your risk. Don’t worry about stopping it. And there’s no benefit to tapering it.

Toffodog profile image
Toffodog

Following a heart attack in May my cardiologist informed me that I would be on clopidogrel for 12 months and then I can stop , no need to taper off them,I also had a heart attack in 2018 and came off clopidogrel and like ms y others on this group had no problems.

Survivor1952 profile image
Survivor1952

My GP was adamant that I stopped my blood thinners in one go, no taper and that the date was also absolute.

I had no issue at all, in fact I was glad to stop, that was nearly 6 months ago.

bikerider00 profile image
bikerider00

In some of your further responses, you've talked about it "managing the risk". Depends what you mean. If you have a stent fitted you are specifically prescribed the the anti platelet (in this case clopidgrel) in order to minimise the risk of a clot forming around the stent. It is a foreign body after all. However, over time your own tissue forms around the stent. And hence the risk of it triggering a clot forming dissipates. I believe this takes around 3-12 months, and hence the prescribing for a 12 month (only) period.

It isn't managing the risk of a heart attack: it's targeted at preventing the stent from causing a clot to form until that is no longer a risk.

Comfycousin1 profile image
Comfycousin1 in reply tobikerider00

Thank you

momander profile image
momander

Hi,When I had my first heart attack I was in clipidogrel for a year, then taken off it . I still take aspirin. I've had 2 further heart attacks and a double cabg, and the same happened. It's a psychological thing isn't it? It was with me. You will be fine though honestly. No tapering off, just alright off it. You will probably be on a beta blockers and a statin as is normal, so these should be enough to keep you right. You will be ok , honestly. Xx

Comfycousin1 profile image
Comfycousin1 in reply tomomander

Thank you. Yes still on aspirin, beta blockers, statins etc... its definitely psychological.

momander profile image
momander in reply toComfycousin1

I remember getting blood thinning injections every day before my heart bypass, until the night before, then none!! I was petrified I was going to have another heart attack!! I think I had in my mind that these were preventing me from being poorly, and so I relied on getting them every day!!

Comfycousin1 profile image
Comfycousin1 in reply tomomander

Yes, pretty much sums up how I feel. The brain is in overdrive. I'll be ok.

Avagra profile image
Avagra

12 months on it then completely stopped as instructed and bruise free with no problems at all 🙂

Comfycousin1 profile image
Comfycousin1 in reply toAvagra

Thank you

Singingforever profile image
Singingforever

I had my NSTEMI at the beginning of July and was told I would be on Clop for one year. But I am not on aspirin because of stomach problems. I am however on Edoxaban because I have atrial fibrillation. I will wait to see what they suggest when the year is up.

Qualipop profile image
Qualipop in reply toSingingforever

I too have stomach problems so I take enteric coated aspirin that does not dissolve in your stomach.

Singingforever profile image
Singingforever in reply toQualipop

Thanks for that. I will discuss with the medics when the time comes to go off the clopidogrel.

Walkingshoes2 profile image
Walkingshoes2 in reply toQualipop

I also have stomach issues. The cardiologist stopped the aspirin and told me to continue with the clopidogrel as it is much kinder to the stomach .

Qualipop profile image
Qualipop in reply toWalkingshoes2

I asked about doing that. I was far happier with clopidogrel but mine said no because they have so much more experience with aspirin.

Walkingshoes2 profile image
Walkingshoes2 in reply toQualipop

That's a shame. I had stomach issues before the aspirin, but it only added to my suffering. I still have issues, but I can honestly say that the cardiologist keeping me on clopidogrel and stopping the aspirin was the best option for me. I know we're all different so some will have no issues with aspirin at all.

Qualipop profile image
Qualipop in reply toWalkingshoes2

Yes I was far better on clopidogrel but they wouldn't play ball. I guess aspirin's a lot cheaper too but I am ok with the coated type.

Walkingshoes2 profile image
Walkingshoes2 in reply toQualipop

I tried 3 types, dispersible, ordinary and the coated ones. Of them all the coated was the better option, but not great. As you've got stomach problems, I'm surprised that your consultant won't change it for you. Hopefully you'll be able to manage on the coated ones without too many problems, if not it'll be worth asking again. Fingers crossed for you and I hope you get sorted.

Comfycousin1 profile image
Comfycousin1 in reply toSingingforever

Thank you

Jerrahem profile image
Jerrahem

hi i stopped 1 month ago under doctor advised. 1 year after

Comfycousin1 profile image
Comfycousin1 in reply toJerrahem

Thank you

PaliGap profile image
PaliGap

In my case I had a stent fitted in January and went on dual antiplatelet therapy. However the clopidogrel was just for 6 months (but aspirin permanently). There was no tapering off.

Comfycousin1 profile image
Comfycousin1 in reply toPaliGap

Thank you

mikealford profile image
mikealford

I just stopped with no problems from stopping. My stents are still okay since Xmas 2017 and I'm 78.

Comfycousin1 profile image
Comfycousin1 in reply tomikealford

Thank you

Cruise1 profile image
Cruise1

Came off clopidogrel 12 months after my stents. No problems. I just take coated dispersible aspirin now instead of aspirin and Lanzaprazole. I buy it from Home Bargains.

Comfycousin1 profile image
Comfycousin1 in reply toCruise1

Thank you

Velda1 profile image
Velda1

I was on Ticagrelor blood thinner after HA in September 23. In September 24 I was taken off as only on for year. I think this is normal practice for all blood thinners. They leave you in Aspirin. I had no issues coming off.

Comfycousin1 profile image
Comfycousin1 in reply toVelda1

Thank you

Qualipop profile image
Qualipop

I simply stopped. No problems at all. I also had had heart attack and 2 stents a year before. Stopping after 12 months is completely normal. I've been on just aspirin now for 5 years.

Comfycousin1 profile image
Comfycousin1 in reply toQualipop

Thank you

Mlinde profile image
Mlinde

I was put on clopidogrel after an HA and stents fitted, and put on it for a year and couldn't wait for the year to end! In fact I've been through it twice. I really wouldn't worry. If your doc thought you needed to continue they'd tell you. Apparently, it's used to assist in getting your heart used to the stent/s.

Comfycousin1 profile image
Comfycousin1 in reply toMlinde

Thank you

Sooty2020 profile image
Sooty2020

Hi. I was on Clopidogrel for 12 months after my stent and now 75mg aspirin for rest of life. No issues. Happy with stent keeping my artery unblocked and aspirin helping the blood flow nicely.

Comfycousin1 profile image
Comfycousin1 in reply toSooty2020

Thank you

pasigal profile image
pasigal

I stopped clopidogrel after 12 months, am now on plavix (aspirin did NOT agree with my stomach). No problems.

Comfycousin1 profile image
Comfycousin1 in reply topasigal

Thank you

1a2b3 profile image
1a2b3

hi there. It seems cardiologists differ on what they prescribe in cases like this . My mother’s cardiologist stops aspirin and continues the clopidogrel. Mine does the opposite . He said they both do the important job of anti clotting , but feels clopidogrel gives more heart protection than aspirin does . At one time, aspirin was the more affordable option and readily available but now clopidogrel is more affordable and therefore he prefers this option . Also, if you can’t tolerate the aspirin, clopidogrel is the other option.

Comfycousin1 profile image
Comfycousin1

I can tolerate both. I will remain on aspirin.

Hoocher62 profile image
Hoocher62

I was on apixaban and tricagrelor after my HA. Both stopped immediately after 12 months which just left the 75mg aspirin. 5 yrs later I'm fine. They only put you on them until the stent had bedded in properly which is 12 months.

Comfycousin1 profile image
Comfycousin1 in reply toHoocher62

Thank you.

Furryears profile image
Furryears

Hi I was taken off clopidogrel too after 12 months after my HA and bypass

I take aspirin I have been ok speak to the cardio team if your feeling unsure they will be able to set your mind at ease

Take care

Comfycousin1 profile image
Comfycousin1 in reply toFurryears

I have now spoken to the cardiologist. Most people here say its fine too. Thank you

Green1964 profile image
Green1964

I had a stent fitted 3 years ago and was told I will be on clopidogrel for life as I can’t tolerate aspirin I always Thort after a heart attack you would stay on them for life unless they just tell u to keep taking aspirin

Comfycousin1 profile image
Comfycousin1 in reply toGreen1964

I'm taking aspirin for life. Stopping clopidogrel.

treya profile image
treya in reply toComfycousin1

Anyone suffer anxiety . I’ve been started on low dose sertraline . Had a heart attack 18 months ago No damage to my heart . Meds for life . Never smoked , not overweight etc . Would like to converse with a like minded event ? Thankyou

Rockcity2009 profile image
Rockcity2009

Hello Comfy,I am on the same medication,I have no problem taking it,and if it was me a,I would just continue on with the medication,Good Luck

Comfycousin1 profile image
Comfycousin1

They are stopping my clopidogrel after a year. I won't be able to continue it. Hence my comments.

CarolingTeacher profile image
CarolingTeacher

I received a stent in February 2023 and was told to stop the Clopidogrel earlier this year. I was pretty scared to stop, but like you my cardiologist, regular doctor, and pharmacist said to stop. People on BHF agreed. So with some anxiety, I cut back on it a bit gradually, added low dose aspirin as recommended by my cardiologist, and stayed on Xarelto…my other blood thinner. (I am a blood thinner for life girl because I have thick blood and I had a pulmonary embolism in2019.) I am happy to report that I didn’t have any problems at all. I wish you well!

Comfycousin1 profile image
Comfycousin1

Thank you. I'm already on aspirin too so should be covered.

Andyman profile image
Andyman

I was in them for 10 years because I couldn't take some other pills. But it was decided to stop them with agreement between my GP and cardiologist. Stopped them straight off with no issues.

Comfycousin1 profile image
Comfycousin1

Thank you

treya profile image
treya

hi . From what I understand , you start on aspirin and clopidogrol and stop one of them after 12 months depending g on your consultants choice . I was told that they both do the same thing but clopidogrel is kinder to your stomach . My consultant stopped the aspirin after 22 months . I had a heart attack 18 months ago just out of the blue … never smoked etc . Had a stent fitted too . How’s your anxiety ?

treya profile image
treya in reply totreya

Sorry 12 months not 22

Comfycousin1 profile image
Comfycousin1 in reply totreya

Sorry I've only just seen this reply. I'm still a bit shaky but I have another month's clopidogrel to see me into the NY.

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