Isosorbide Mononitrate

[Frogman9]

HiI'm on Isosorbide 40mg twice a day, I have been taking one at 6:45Am and the other at 17:30 pm is this the correct way to space them out?

[Lowerfield_no_more]

You should talk to a pharmacist who will be qualified to answer.

[Ennasti]

Definitely a question for your pharmacist or doctor. I only take mine once a day.

Generally speaking, drugs taken twice a day are best taken at the same time each day and 12 hrs apart.

I take both eliquis and carvedilol twice a day and take them roughly around 8:30am and 8:30pm but I’m not stuck to these times. It’s often earlier or later with either and both!

[Milkfairy Heart Star]

I have been taking Isosorbide mononitrate for many years.

You can develop a tolerance to nitrates which means that the nitrate isn't as effective. For this reason it's important to have a nitrate free period in 24 hours, rather than taking your isosorbide nitrate at 12 hour intervals.

I personally take my isosorbide mononitrate 60mgs at 6pm and then another 60mgs at 11pm.

I also use GTN patches which I put on at 6pm and remove the following morning.

I do this as I have vasospastic angina and experience most of my chestpain at night.

I suggest you talk to a Pharmacist, your GP or Cardiologist to determine what is the best time for you to take your isosorbide mononitrate.

[Crystal614]

I take 60mg of Isosorbide Mononitrate a day. On the advice of the pharmacist, I take half the dose at about 5am and the remaining 30mg at 8am. She told me that it is important to have a nitrate free period, also mentioned by Milkfairy with her reply to you.

[Wingnutty]

I take 120mg all in the morning at the same time as this is what I am instructed to do.

[Frogman9]

Just had a word with a local Pharmacist and she's told me 6:45AM and 2 or 3 in the afternoon would be fine. Thanks for all the replies.