Stopping PPI?

[Heartmum56]

Hello everyone, I'm approaching a year post Nstemi with one stent and thus the end of ticagrelor hourray! What I am wondering is if I am then down to aspirin as the only blood thinner (plus ezetimibe and atorvastatin long term but hopefully not much longer on bisoprolol and ramipril ) do I still need ppi? Has anyone swapped to enteric coated at that stage and dropped the ppi?

[BlackGazelleHound]

After I stopped ticagrelor I switched to enteric coated aspirin and stopped PPI. 2 years on and I am doing fine, no stomach issues. Of course we are all different and so my advice would be to ask your doctor and/or pharmacist to change your aspirin to enteric coated and, with their agreement, stop the PPI for a trial period to check that your stomach remains comfortable without the PPI.

[APC65]

I stopped PPI as soon as stopped my clopidegrel - now just enteric coated aspirin . Consultant and pharmacist all very clear no need for PPI once finish dual platelet therapy - usually 12 months. However advice was gradually reduce PPI as can get rebound effect, take gaviscon to help manage which body gets used to normal levels of stomach acid again.

[Heartmum56 in reply to APC65]

Can you explain a bit more about how you reduced the ppi?

[APC65 in reply to Heartmum56]

Hi - I was taking 30mg Lansoprazol daily. First I split the dose to 15mg twice a day rather than 30 once a day - to give flexibility.... And get GP to prescribe the lower dose. I then reduced to 15 mg daily, then 15mg every other day.... It's then onto use as and when need it, until off it completely. Doing it this way I had very few issues with rebound acid. I reduced the dosing over about a week each time before stepping it down again.

[Ennasti]

I stopped cold turkey and did have a few flare ups in the first few weeks. I was advised to take the PPI as a PIP when needed so I took it as advised and didn’t have any issues. I still take it as a PIP once in a while but rarely need it. I take magnesium and I’m convinced it helps keep any heartburn at bay.