Hiya, I’ve been prescribed indometacin 25mg 3x a day and omeprazole 20mg 2x a day for possible trigeminal autonomic cephalalgia syndrome ( I need to do more research on this ) I think it’s basically occipital neuralgia and I’m already on 2.5mg bisoprolol and 5 mg Ivabradine for my heart.
Does anyone else take a similar concoction of meds? I swear I read that it wasn’t advised to take Ibuprofen with beta blockers? indometacin is basically a much stronger anti inflammatory med. I’ve only been told to take it for two weeks as there’s a risk of gastrointestinal bleeding and renal impairment.
obviously I trust all my doctors but I’m only 19 and my parents are concerned about all the chemicals going into my body from the meds. Just wondering if anyone else is on anything similar with their heart meds, thanks 🙂
The main heart medications I am on are Bisosoporal, Lisinopril and Atorvastatin. For my sins I also suffer from arthritis I have been told quite firmly that Ibuprofen and Naproxen are definite no-nos. In addition I have been told to avoid over the counter cold and flu remedies.
Someone on more similar medication may be along in a while.
Thank you for replying Michael, it’s all just a bit confusing! when I see my cardiologist il ask him what he thinks as my GP said it was fine to take these meds with the bisoprolol as well as my neurologist, i also have no clue if the Ivabradine will interact as nobody seems to know what Ivabradine is, Im my GPs only patient on Ivabradine. I’m sure il be fine because if they were concerned I wouldn’t be on the indometacin.
Hi. I’ve been taking Indomethacin since July as a preventative for rare Indomethacin-responsive migraines, possibly hemacrania continua. I take 25 mg a.m. and 25 mg p.m. It is imperative that you take this heavy duty NSAID with food to help prevent side effects. (Same applies for any other NSAID.). I never take it without a bit of food first, followed by a bit more food, to assure my stomach is protected. I have had no ill side effects thus far from Indomethacin.
If you are concerned about drug interaction between medications you’ve been prescribed, please look up your medications on drugs.com. Enter Indomethacin, click interactions, and scroll through the alphabetical list to see if any of the meds you take interact. This website gives a color coding to the severity of drug interaction. I always cross reference all of my medications for contraindications because doctors and pharmacies do occasionally make mistakes. I do have several different medications that I take that come with a drug interaction warning that no doctor or pharmacy warned me about. They are all migraine preventative or migraine treatment meds, except for one. They all increase seratonin, so if I took two or more at the exact same time, I could end up with seratonin syndrome and in the ER. All are dispensed to me at low dose, but still very strange the pharmacy has not warned me about taking all of them at the same time. Better to be safe than sorry and always check your medications for interactions yourself.
Disclaimer: I actually just joined this group so I could respond to your post. It’s 4:00 am where I’m at. I was just searching on Indomethacin because I am having a surgery this week. Indomethacin, like other NSAIDS thins the blood, so technically I was supposed to go off of it. The surgeon wanted me to, of course, but I explained that I get a migraine if I skip just one dose. All of my body pain also comes back with a vengeance, I can’t bend my arthritic fingers very much and they really hurt. I tried stopping Indomethacin for one day, and it was a disaster. I was in so much pain! The surgeon gave me permission to go back on it, but I woke up in the middle of the night worrying about bleeding problems during surgery. Hence my search here.
Indomethacin truly is a miracle, life changing medication for me. It has allowed me to have my life back. I hope you find the answers you need about Indomethacin combined with your other medications.
Thank you for you’re reply! Yep I’m making sure I’m taking the meds with food,indometacin has so far helped which is great! I’ve got one more week left on it which is scary as I don’t want the neuralgia to come back 😬 I’ve tried searching everywhere for drug interactions but no luck as I believe Ivabradine is a newish medicine. I wouldn’t worry too much about you’re operation ( even though it’s hard not to) the surgeon is highly trained and has probably had many patients on blood thinners and all sorts of meds it’s exactly what they are trained for! Good luck for this week.
You are welcome, Hidden . I found a lot of information for you about Ivabradine. Drugs.com says there are 325 medications that interact with Ivabradine. drugs.com/drug-interactions...
Here is more information on Ivabradine, including another list of interacting drugs on the Prescribers Digital Reference website. Good news: Indomethacin is not listed as being contraindicated.
Thank you. The anesthesiologist called me today and he set my mind at ease. While we were talking my doctor texted him that it is ok that I remain on Indomethacin. The anesthesiologist explained that when it comes to patient's with severe migraine disorders, it's best not to restrict them from their migraine preventative medication because that can make recovery more difficult to manage. I like their train of thought!
Is your TAC trigeminal neuralgia, or a different one? I completely understand your concern for the pain coming back once the one remaining week on Indomethacin is over. What is your doctor's plan for treating you for your TAC once you are off Indomethacin? I hope they are not just going to stop your meds without another plan. Is there any reason they will not keep you on Indomethacin since it is working? Once you're off the med, the pain will come back because results are not permanent. Have you contacted your doctor to what else you'll be treated with?
There is hope for relief with other medications if you are not allowed to continue on Indomethacin. I really need to find a backup medication in the event that I can no longer take my life saver Indomethacin. Other medications used for TAC's are anticonvulsants (same as antiepilectics or antiseizure medications) such as carbamazepine (has very good reviews for use on TAC's), lamotragine, oxcarbazepine, pregabalin (Lyrica), topiramate (I tried it and did not like it). Medications for nerve disorders, such as clonazepam and gabapentin (has good reviews). Some antispasmotics (muscle relaxants) such as baclofen. Here's a link of reviews of some of these medications for TAC's:
Cymbalta (duloxetine) is an antidepressant often prescribed for neuralgias. Amitriptyline is a tricyclic antidepressant that is used successfully for some migraine disorders as a migraine preventative. In addition to Indomethacin, I take another migraine preventative that is close to Amitriptyline, called Nortriptaline. I take a low dose 20 mg at night. Several types of nerve blocks or nerve surgeries are used as treatment. Neurotoxin (Botox) is also used. I've had botox for migraine once before and it helped quite a bit. I am getting Botox again in a few weeks. If you are not allowed to continue on Indomethacin, I hope that you are given the opportunity to try some of these other treatments for TAC.
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I found a lot of information for you about Ivabradine. Drugs.com says there are 325 medications that interact with Ivabradine. 
Medication or no medication 
Multiple cardiac medications 
Should my medication stop?
Arthritis medication 
Medications causing mouth ulcers?
