Change from Nucala to Dupixent

[kdr112]

Hello all! I don’t post much but read daily. I have eosinophilic asthma and chronic sinusitis. I’ve been on Nucala for the last 5 years and have been relatively well controlled. After a mild case of covid I developed bronchitis and was treated, but after that, I can’t seem to stop coughing. I have constant sinus issues and generally feel like I have a bad cold.

My Pulmonologist has recommended taking me off the Nucala and putting me on Dupixent. Has anyone made this change and if so did your asthma and coughing improve?

Thank you so much!

[Subicbay]

For many years, I have been suffering from chronic sinus infection, eczema and asthma due to environmental allergies. I have been on Dupixent for over 2 years. Dupixent got rid of nasal polyps and my asthma was under control. But for the past 6-8 months, I have experienced severe headache, blurry vision and joint pain. One of the side effects of Dupixent is Blepharitis, headache and joint pain. My rheumatologist told me to stop Dupixent until farther notice just to see if my condition improve. It did. My headache had calm down. I'm on ocusoft for Blepharitis and Xiidra for dry eyes which i believed are side effects of Dupixent. My allergist is switching my med from Dupixent to Nucala. My concern is Nucala may have the same side effects as Dupixent. I'm undecided whether to take Nucala my concern is the side effects that I had experienced with Dupixent.

Does anyone in this forum have the same experience? Thanks.

[kdr112 in reply to Subicbay]

I’ve been on Nucala for several years. I have a bit of tiredness the day after my shot and some muscle cramps in my legs for about a week. Nothing very bad. I’ve decided I’ll stay on the Nucala vs changing to Dupixent, mainly for 2 reasons, cost and I’m doing well with the Nucala.