1st inhaler stopping 2nd working?

[Matman]

It might be that using one of your Inhalers ‘too soon’ before (or too soon after) your ‘other inhaler’ is reducing - or increasing - the potency of the second inhaler.

If you’re in the habit of using one inhaler, then - less than two hours after - using a different one, the chemistry of the first drug might be effecting the chemistry of the second.

That might result in you getting less benefit than you should be from the second inhaler (or conversely, too much potency).

Least, that seems to be what’s implied by the message you’ll see if you scroll down the short page after visiting the Site linked-to below. (Something to think about).

emphysema.net/inhaler_seque...

[WheezyAnne]

Interesting read. I think I will experiment with my timings, see if it makes any difference for me. Nothing ventured, nothing gained. Thanks.

[Matman in reply to WheezyAnne]

Important thing is knowing the best option if having a serious attack. Maybe ask Pharmacist / GP.

[CDPO16]

One doesn't always know what to do for the best, advice varies source to source. I was told to use Ventolin 15 minutes before my dose of Fostair to open up the airways to make the Fostair more effective. This advice came from a respiratory nurse and also at pulmonary rehab.

[Matman in reply to CDPO16]

Im in the habit of doing the same if having a rough time, but I try, where possible, to stretch the interval to at least 30 Mins.

I was told once that, in emergency, could put my Fostair Dose in Spacer along with Ventolin

[Hidden in reply to Matman]

Fostair can be used as a reliever. I was struggling with my asthma as I had an infection that had been cleared up. I was informed to use my fostair 3 times a day not my blue.

[Matman in reply to Hidden]

I’ve sometimes found Fostair works better as a reliever (not just prevention) in situations where Ventolin hasn’t ‘seemed’ to help much.

Also found that you can use ‘both’ for relief if things are bad.

Only issue is, when taking multiple doses of Ventolinn in a Spacer, in an erergeny (i.e. in a similar fashion a nebuliser might be used in during an emergency) I was told I can put upto 10 Doses of Blue Inhaler all a once. However, where Fostair is concerned - because it contains a LABA rather than a SABA - I would be very apprehensive about doing the same for that. Especially when the Maximum Medically Licensed Daily Dosage of a Fostair 200/6 is 4 Puffs a Day (Fostair100/6 being 8 Puffs). In an Emergency, if you did 10 Puffs of Fostair (whether 200/6 or the 1/6 Fostair) you’d exceed the Licensed Amount. I’d be just as concerned about the Formoterol in the LABA at such High Doses, whereas Ventolin Multy Dose Use (emergency size doses) seems to have been sanctioned / permitted by someone.

[Hidden in reply to Matman]

I have now dropped back to the two morning and two at night. I can go down to one in the morning and one at night. I only go by doctor's orders. When I am taking my fostair 3 times a day

[WheezyAnne in reply to CDPO16]

Me too.

[Dionysius1662]

Thankyou for this info, I hadn't thought of that.

I will space my different inhalers better and give it try.

Surprising what you came up with, whereas I did not think of this.

Thankyou.

Here's hoping.

[Matman in reply to Dionysius1662]

Could check with Pharmacist I guess.

[Hidden]

It doesnt show how they have come to this conclusion. Is there a clinical study anywhere to back this up?

[Matman in reply to Hidden]

Not heard of a study. As bio chem reactions are very sensitive seems intuitive that one drug could very easily modify the processing of another. Certainly when you read cautions in Medicine Leaflets about what not to take alongside the drug the leaflet covers, it’s obvious that one Med often effects another. You see similar cautions on drugs.com when you look something up.

Given that inhaled drugs go straight to the Site of primary action, I would guess that a reasonable interval should be allowed between different inhalers.

If there’s no reason not to allow at least a respectable amount of time inbetween, could be a good idea to do so. Problem is what to do if having a serious attack. Best to ask GP / Pharmacist I guess.

[Hidden in reply to Matman]

I agree with what you are saying but without a trial of some sort, even a dozen people, this is just some ones opinion, it could be right or just as easily be wrong.