Had to change from Apixaban to Edoxapan due to severe reaction of itching all over the body, it was really bad. The Edoxapan is much better, but still get the occasional real itches on back and legs . but they gave me E45 anti itch cream that REALLY works well and often stops after a few minutes after first application. This is different to the normal E45 cream , it is entitled E45 ANTI ITCH CREAM so don't confuse the two ok .
You can get this as a repeat prescription item if you are a suffer also
Thought I would share this