I took amiodarone for 3 1/2 years and developed severe hyperthyroid. Currently taking 40mg prednisone and just added methimazole to try and control that. I was changed to Sotalol 80mg twice a day initially and then upped after having break through to 120 twice a day. 3 days later at EKG EP said to up to 160 twice a day. After a week on 160 and feeling miserable I reduced back down to 120. I had a break through with 160 and just felt such tightness in my chest. The hyperthyroid causes anxiety along with the prednisone so sometimes I don't know what's causing what. I am also taking eliquis, lisinopril and amlodopine. Just wondering what other experiences with Sotalol have been.