What's best for ostoepenia: LIFTMORE Study-type exercises, prolia, zometa, or something else?I have mild osteopenia. The oncologist offered Prolia but it has a 2.7/10 rating on webmd and drugs.com. Zometa has a 4.8/10 rating. Most people gave 1/10 ratings for Prolia. Zometa wasn't much better. I read and watched videos that exercises that have impact, like in the LIFTMOR trial, and other type studies, showed some reversal of halting of degrading bone density. Do any of you have experiences with these drugs, or these non-drug options like weighted vests, heel drops, pullup drops, heavy weights (85% of max) lifting, basketball, rebounding, etc? I prefer the exercise and natural options usually but wanted to hear personal anecdotes. I'm surprised the Onco was in favor of prolia considering the horrible side effect reviews. I already had severe side effects from Levaquin and cv-19 vaccines, so I don't want another terrible reaction. The prolia injection is active for ~6 months, so you can just stop it like a pill. Please, no chatgpt or Grok type search results or hypothesis. I'm just interested in real experiences or study results. thanks,George
What's best for ostoepenia: LIFTMORE ... - Advanced Prostate...
What's best for ostoepenia: LIFTMORE Study-type exercises, prolia, zometa, or something else?
My wife has osteoporosis. She just had an encouraging two-year follow-up bone scan after adding lots more greens, and more calcium and strontium to the supplement regimen, and minimizing oxalates intake. But by far (!!) the biggest change she made, and I believe the biggest lever you have, is strength training. Load the muscles and the bones will respond too.💪
Also got some good information from (greatbonesconsulting.com/) Dr. Keith McCormick's book.
I think Ive seen some videos from McCormick. I'm defintiely going to read and study his program. I never worked on targeted bone density before because my routine at the gym took care of things, but I've been at my mom's house helping her for 17 months and got away from the heavy weights and impact exercises. Thanks for the helpful response. One last thing - I don't take calcium because that contributed to my coronary heart disease. A doctor told me to supplement it in 2000. 13 years later, I had prostate cancer on CAD. In 2000, the dermatologist also told me to stay out of the sun, after I had some skin cancer removed. Lack of D3 and excess calcium contributed to my demise.
Yeah, too much calcium supplementation is not a good thing either. Way beyond my pay grade to know how much is too much and when it can be detrimental. Obviously getting calcium naturally (leafy greens, nits, beans, sardines with bones [if you eat those], etc..) is best and I've read that a calcium supplement from algae is less likely to result in any coronary issues, but who knows?
FWIW, we supplement with D3/K2 (as MK-7) and strive to keep D levels around 75.
We found McCormick was very accessible for a phone consult, but that was a couple years ago and I don't know about now.
Get back in the gym and throw some weights around !!👍
I got osteoporosis from the ADT so get zometa infusion every three months. Works great and minimal side effects which for me were just feeling a bit like having flu for a few days after the first infusion. Easy to get done and so that would be my vote. I’m advanced stage 4 and have been having the zometa for over 2 years now.
Good to hear that the zometa is working for you without the bad side effects that many others get. Stay strong!
Exercise more and more specifically. I would just monitor the osteopenia. Those drugs are best to add as a last resort for a number of reasons.
I think that's a good way to start London. Thanks for the input. I can check the dexa a year after doing the workouts. I dont think the doctors know the intensity of my workouts and athleticism. I just need to break free from giving care, and hit the gym once a day.
I have been getting 120 mg of denosumab injections every three months since January 2020. I don't know what the brand is. No side effects that I can identify, but we did take a year break about three years in.
However, every two years I do a bone density scan and I seem to lose 2% ground each time. I've been trying to convince my MO to add low dose estrogen (staying on denosumab) to see if we can correct that issue, but he seems terrified of the word "estrogen." He still harkens back to the days of oral estrogen and cardiac issues even though I bring him article after article about the transdermal patches. No success yet, but I keep telling him that this issue (and others he is behind the curve on) won't just wither away by themselves. It may be his clinic protocol that's the problem.
Anyway, that's my experience
Thanks man. What city is your doctor in? I think 90% are not up to date on things that they perceive are in the past. One of the guys on estrogen lives in Thailand, and he's happy with the patches. Do you have a link that shows evidence that estrogen patches don't cause cardiac issues. I have coronary artery disease, but I don't think it's gotten any worse since I adopted a strict diet plan after I got diagnosed with cancer and CAD back in 2015. Are you doing any impact exercise training regularly, like the LIFTMOR study exercises?
George
Daytona Beach area. Our county is now 5500K people plus it borders Sanford/NE Orlando, but we seem to lag behind a bit on cutting edge knowledge.
I don't have the studies handy, but try Googling estrogen vs ADT in the latest clinical trials. I'm pretty sure they address that issue. If you have trouble finding, let me know and I'll search around. The PATCH trial is one such trial reporting very recent results.
I do walk with 4-pound weights in each hand, 3-4 miles several times per week (walk five days per week). I take stairs and sometimes our condo gym. I could always do more and heavier on the resistance side. I'm also getting into doing full squats. Not easy at first, but you can improve quickly; just steady yourself if you are new to it.
Second London. At your level exercise. Things like hopping, resistance and balance exercises, etc.
Third! Sometimes I just put a 20 vest on late night, and do jumps around the room, hops, and jumping jacks too.
Been taking Prolia for three years. Had a two year follow up bone density scan and had a 7% increase in density. No side effects.
7% increase in density/strength is excellent. I wouldn't mind using the Prolia but I'm concerned about the bad side effects that many get. I might try focused exercises for one year, and if that doesn't improve my density, then try the prolia.
Hello GeorgeGlass,
I have been taking pure Glucosamine, nothing added, for many years. Before being diagnosed with this Beast, I was diagnosed with celiac condition, coupled to that was osteoporosis.
I started taking the Glucosamine to try to keep the bone loss at bay, but recently I had to have a bone density scan in preparation for a replacement knee. Comparing the findings to a previous scan, taken by the same centre, it showed an increase in bone density.
I didn't elaborate, unless it's a pill or a jab, it isn't worth a mention. It is not an instant fix, I did at some point get something from my Onc, it made me feel as sick as a dog, so I stopped it.
The advice here to exercise is good, eat your Greens, like Mum told you to, but this might help you too.
All the best.
I often take my glucosimine sulfate capsule, usually one capsule every other day. It's 750mg in one capsule. That's probably not enough. What amount do you take for day? Is yours glucosamine sulfate?
George
Hi George, the measuring spoon says 1.5 grm, its powder form. That's daily, I stir up in a yogurt. Phil
By George............. nice to see you. I take prolia and feel lowlia. So when I tell people I'm 88 they ask me how I feel? And I respond "Like I'm 88".
Keep posting.... and remember work in while working out.
Good Luck, Good Health and Good Humor.
j-o-h-n
lowlia lol. No bad side effects from prolia? Nice to see ya too. Still busy here helping my mom all the time. I do exercise at night, in the house, but it's not good enough. Orgovyx and nubeqa require a stronger exercise routine to combat the bone density loss. 88 is great John. You had a nice long life, and hopefully many more years. Remember, on occasion, you can drink a few glasses of wine and show your bone strength on the dance floor. You'll be a commercial spokesperson for Prolia, by George 
George
Helping your Mom now automatically entitles you to a partially used set of angel wings in the future. Hopefully they refrigerate them so they stay fresh until you need them by the year 2075. Now ask me who originally wore the wings and finally traded them for a golden halo. It was Mr. Rogers who left the neighborhood.
You're right, about me experiencing a nice long life, It was due to the fact that I began embezzling at a very young age. My method was 9 mils deposit n the company's bank account and 1 mil in my pocket for me. That's now called "The easy peasy method".
Unfortunately I do not partake of the evil devil's drink if it contains alcohol but look out kitchen door if ice cream is being served (especially chocolate chip/two scoops). Those ice cream calories are what affords me the time and strength to non-stop dancing. I presently am a spokesperson for ice cream and naked women. BTW I happen to love my job......
Take care and you have my kind regards.
Good Luck, Good Health and Good Humor.
j-o-h-n
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