Whack-a-Mole

[jfoesq]

Apologies in advance if I posted something similar a few days ago, but I didn't receive any responses and thought the post probably did not get published.

Age 66 and on ADT for 12+ yrs. Did whack-a-mole to largest tumor 2+ yrs ago when it appeared on PSMA scan to be responsible for PSA rise from undetectable to low numbers (less than 1.0). PSA went back to undetectable again and lasted about 6 months before becoming detectable and rose over the last 18 months or so, and most recently almost doubled over an 11 week period from ,20 to .35. Last weeks PSMA showed some increase in one of my several (4-5) tumors. The tuor was 1 of 2 in my vertebra.

I am meeting with my MO tomorrow to discuss how we should proceed and am wondering if whack-a-mole (radiation) is an option for a vertebral tumor WHEN it is not presently causing me any pain. Of course, regardless of the answer to this question, my MO and I will be discussing adding and/or modifying my present treat of Lipitor and Abiraterone. ( I just read about some positive phase 2 results in a specific type of 177 Lu-PSMA-I&T study published in Onclive.com that I will raise with her

Thank you in advance for your responses.

[CANAMA]

In June 2017 SBRT was applied to two spinal vertebrae from which I had not experienced any pain. The treatment was considered successful and has not been repeated.

[jfoesq in reply to CANAMA]

Excellent. Thx

[MarkBC]

I'll be watching for responses and I hope you post what your MO says. Our situations are similar. 61 years old. 6.5 years of treatment. Eligard and abiraterone. PSA is slowly rising from undetectable. Current PSA is 0.03. Recent bone scan shows possible growth in one tumour. No pain. I see my MO in January.

[jfoesq in reply to MarkBC]

I will let you know what my MO says and recommends about whack a mole and other treatments.

[mrscruffy]

I have had numerous mets up and down my spine. Never had any pain. All have successfully been radiated