Had slight increase in PSA after 4th cycle of chemo - is it worrisome?

[Samrecan]

Started Triplet-therapy (Lupron + Nubeqa) then added Chemo Docetexel 6 cycles on August 22, 2024 (3 weeks apart).

Before chemo 20-Aug-2024: PSA 5.02

After 1st cycle 10-Sep-2024: PSA 3.1

After 2nd cycle 01-Oct-2024: PSA 2.09

After 3rd cycle 22-Oct-2024: PSA 1.49

After 4th cycle 12-Nov-2024: PSA 1.52

I am really worried about the slight increase in PSA after 4th cycle. Please advise.

[Teddy28]

that is a meaningless increase. There are variations in testing that will cause changes in PSA . Don't give this another thought.

[Nusch]

I wouldn’t treat this as any form of increase. Look forward to your next check positively, you respond well to the treatment.

[j-o-h-n]

We always worry when the meter goes up....even if it's just 3 points....Just think of it as half time and the opposing team got a field goal to take the lead.....There's plenty of game left.....

Good Luck, Good Health and Good Humor.

j-o-h-n

[Samrecan]

Thanks everyone for your encouraging comments.