4 months in and surprised at how poorly I am feeling.

[MedicaMahnJahm]

Gleason 9. ONC states Very High Grade with metastasis to local LN and LN above aortic bifurcation. (bones clear per PSMA).

PSA drop from 22.8 to .4 (good).

Treatment plan:

1 month bicalutamide then

Eligard and Zytiga combined.

Radiation 28 sessions

1 week after fiduciary markers placed, I was admitted to ER with a bad UTI. Painful peeing with blood and tissue matter. AGAR plate showed e-coli! WTF?

One week after 2nd Eligard injection a weird headache showed up. When I would bend over, instant pressure migraine that goes away quickly. Stand up after driving to 1st Radiation treatment, instant pressure migraine. Accidentally bump head getting into car, same thing. Plus I had chills. Like a flu. Spoke to doc after 1st rad treatment. She said go see PCP or Urgent Care. Urgent Care saw me and sent me to ER.

ER ran tests (Head CT and CT with contrast, blood etc.). No strep. No flu. No COVID. Admitted to hospital. They ran an MRI with contrast. Brain OK. ONC doc must have heard I was in hospital and shut off Zytiga. Still have chills but migraine thing subsided at hospital. No clue what caused it.

4 rad treatments done and aside from general tiredness (already), I have this odd lump/heartburn feeling in my chest. Concern because they are zapping a couple LN near my decending aorta. Doc and other assure me it is OK to to so.

So....I don't have a good feeling about this, but at the same to I am questioning my feelings. Am I being a baby and should just suck it up?

Anyone else had a similar experience?

Sorry for the wall of text.

[HaMoon]

I was on a similar course of treatment, with more radiation. Radiation made me tired, but the bad headaches came from Zytiga. That medication caused very high blood pressure. Tried smaller doses but same result. Once I stopped taking it the bp dropped to normal and I felt much better. Sounds like you may be having the same reaction.

Started Xtandi in place of Zytiga and have been fine on that.

[MedicaMahnJahm in reply to HaMoon]

TY!

[j-o-h-n in reply to MedicaMahnJahm]

Greetings MedicaMahnJahm,

Would you please be kind enough to update your bio. All info is voluntary but helps you and helps us too. Thank You (and we hope you feel better).

Good Luck, Good Health and Good Humor.

j-o-h-n