0 PSA erection?: I'm on Lupron and... - Advanced Prostate...

Advanced Prostate Cancer

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0 PSA erection?

4tunate1 profile image
15 Replies

I'm on Lupron and Zytiga/Prednisone. So far very successful in dropping PSA levels to undetectable. With this comes the usual side effect of everything being quiet 'down there'.

Recently, I've had erections in the middle of the night. Just a couple over a period of a few weeks. Under normal circumstances, to be expected. While on doublet therapy, this was a surprise.

I'm not running to my doctor to check PSA or anything, but I was curious how this could happen with an undetectable PSA.

Has anyone else experienced this or have any idea how/why? Is it normal, or a problem?

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4tunate1 profile image
4tunate1
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15 Replies
stealthrider profile image
stealthrider

Could be you are lucky or having a testosterone bounce? Guys who had nerve sparing RALP and subsequent undetectable PSA have erections all the time.

Tall_Allen profile image
Tall_Allen

Testosterone isn't necessary for an erection, only for libido.

Cp014 profile image
Cp014 in reply toTall_Allen

Thank you!! I was also wondering. Being I have full erections at will.

Supporting evidence.

Got my psa today 11/12/24. It was.16!!

Was4.1 prior to first lupron inject , 3 months ago.

Thank you so much for all you do!!

Hal900 profile image
Hal900

Same here, although I am taking 5mg of Cialis daily. I was so worried I called my cancer nurse , who told me it’s nothing to worry about and to just enjoy it! Just came back out of nowhere, and now most nights, but there is considerable “shrinkage” , which I guess is from radiotherapy …it’s a great blessing and I feel very lucky, the only problem is finding the desire to do anything with it! …but I will take this small (🤣) win!!

All power to you Warrior!

4tunate1 profile image
4tunate1 in reply toHal900

I'm not taking any Cialis or anything. Just a random event. And yes, considerable shrinkage!

Hal900 profile image
Hal900 in reply to4tunate1

Good that that is without Cialis, I seem to have had a constant runny nose since I started using it !! Maybe I will try a break and see what happens

Cyclingrealtor profile image
Cyclingrealtor in reply toHal900

Have you been on adt/ leuprolide also?

I have had RP, 33 rounds of EBRT radiation and 24 months of leuprolide and 18 months of abiraterone. Shrinkage range is 30 - 40%, would be my guesstimate. I had no idea about this part of the journey. 🙁

Hal900 profile image
Hal900 in reply toCyclingrealtor

Yes, 38 months and counting on leuprolide and enzalutamide…RT 24 months ago. I would say more like 50% loss for me, that and the loss of libido are the worst thing about all of this, the other side effects I can deal with.

EdinBmore profile image
EdinBmore

Suggest ED meds. A study I was in provided 60mg three times a wk. Plus a penis pump. Got to keep the blood flowing. Know that you're probably not interested in sex at all but do your homework (e.g., masturbate) regularly. It will help.

EdinBaltimore

bowmasterguy profile image
bowmasterguy

They have chemicaly castrated you . I am going the same way .

PELHA profile image
PELHA

Husband has T right now of 9 (!) yet still active with help of a daily 5mg Cialis and a half Viagra pill as needed. Sometimes uses a C-Trimix injection. You’re down but not out!!

NemoHic profile image
NemoHic

I've been on ADT and Nubeqa for 14 months and can still get a full erection, although it requires more than a bit of stimulation from my wife first. I didn't have radiation or a prostatectomy, which I'm sure helps. (Did have a TURP, though.) T is about 15 and PSA is less than 0.1.

My wife tells me not to brag to the boys about this, but honestly, I think that she should be bragging to the girls!

j-o-h-n profile image
j-o-h-n

I had one the other night...... and I jumped for joy in the morning until I found out my wife was putting starch in the laundry and it was just my pajama string...

Good Luck, Good Health and Good Humor.

j-o-h-n

billyboy3 profile image
billyboy3 in reply toj-o-h-n

You are so bad Johnny!!!!

j-o-h-n profile image
j-o-h-n in reply tobillyboy3

Will add that to my resume....Thanks....

(Funny, only my family called me Johnny and my brother was called Billy)....

Good Luck, Good Health and Good Humor.

j-o-h-n

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