Quick question about Provenge and PSA. - Advanced Prostate...

Advanced Prostate Cancer

22,349 members28,110 posts

Quick question about Provenge and PSA.

dhccpa profile image
13 Replies

My first PSA reading after finishing Provenge on 9/23 was 2.72 on 10/2.

The last PSA reading just before Provenge began was 1.88 on 9/5. It had been at that level since around June 1 over four readings.

Any possibility that Provenge can cause a rise (temporary or otherwise) in PSA? If so, I haven't read that.

I'll be meeting with the doctor whose clinic I used for Provenge on Tuesday, 10/8, but wanted to get feedback here before the meeting.

Written by
dhccpa profile image
dhccpa
To view profiles and participate in discussions please or .
Read more about...
13 Replies
KocoPr profile image
KocoPr

it could be that your immune cells are killing the cancer cells and spewing it’s antigens throughout. I had a psa bounce 4 days after starting darolutamide a couple years ago.

dhccpa profile image
dhccpa in reply toKocoPr

Let's hope that's it. I wasn't certain what to expect.

KocoPr profile image
KocoPr in reply todhccpa

How are the side effects?

dhccpa profile image
dhccpa in reply toKocoPr

Not much at all other than after second re-infusion. Maybe a little less energy, but hard to be sure.

KocoPr profile image
KocoPr

That’s excellent! Good luck

Tall_Allen profile image
Tall_Allen

Provenge is known to have no effect on PSA.

dhccpa profile image
dhccpa in reply toTall_Allen

That was my understanding. So we'll see where it goes.

JolleySprings profile image
JolleySprings in reply toTall_Allen

What is it’s purpose and who qualifies for it?

dhccpa profile image
dhccpa in reply toJolleySprings

It's an immunotherapy. If you are metastatic and ADT has ceased to work completely, you're qualified.

Tall_Allen profile image
Tall_Allen in reply toJolleySprings

It extends survival. For mCRPC.

JolleySprings profile image
JolleySprings

We just got off of a zoom meeting with Dr. Aggarwal ….

I am pretty discouraged with our conversation.

Because WE ASKED…. He said after cancer becomes metastatic …( my husband’s in the “para aortic abdominal region) Nothing has shown up elsewhere yet. And we are in year 7.

Stats say 12-24 months is the avg time left of life.

Of course he said that was an average.

It seems that isn’t the avg of folks on this forum.

GAdrummer profile image
GAdrummer in reply toJolleySprings

My husband is 15 years with the same nodes only at the same area. So there is hope.

JolleySprings profile image
JolleySprings in reply toGAdrummer

Thank you so much for this encouragement!!! ❤️

Not what you're looking for?

You may also like...

PSA drop after Provenge.

Well, I sure wasn't expecting this. On 6/24/2019 with a PSA of 0.9, I started Provenge. 14 days...

Provenge immunotherapy

After 5.5 years on Lupron (no Zytiga, Xtandi, Daro, etc.), my PSA hit its highest points ever...
dhccpa profile image

Provenge - Supplements to activate modified cells or augment Provenge treatment

I just completed the three infusions of the Provenge treatment. As is seemingly common, my PSA...
tom82 profile image

Provenge

I'm at the 5-year mark on Lupron only (except for moderate demos man). All-time low PSA was 0.5 in...
dhccpa profile image

Provenge Advice

I'm PCa for 13+ years and Stage 4 for the past 3+. On ADT (Lupron or equiv. only). PSA climbed to...
33947 profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.