We just left the Oncologist office and not good news. PSA is still climbing. It went from 64 to 74 in 6 weeks. Hubby has been through XTANDI, Chemo, targeted radiation, RADIUM 223. Been on Eligard for 7 years. Oncologist would like him to go in a clinical trial at Princess Margaret hospital in Toronto, Ontario, before her last option of Chemotherapy again. Has anyone had good results from trials?
You're thoughts and or experience would be greatly appreciated.
Concerned wife
Which trial?
This we don't know yet. We just had the appointment this afternoon and this is her recommendation since she wants to keep his 2nd round of Chemo in her back pocket. She said these are the only two options left. Let me say this though, this is the best my husband, Mel has felt in the past 2 years, so we were surprised his PSA is still going up. He has a bone and CT scan scheduled next week. He will have his PSA checked again in 3 weeks.
Oncologist is putting Ina request to Princess Margaret hospital for Mel to be on the list when the next trial is available.
Let me know.
I will be sure to let you know. Both my husband and I along with so many others respect your knowledge and opinion.
Hello,
I am in a clinical trial at the British Columbia Cancer Agency investigating the use of Lutetium pre-chemotherapy. As perhaps you know this drug has been approved in Canada but only after chemotherapy. My experience with this clinical trial has been outstanding. No nausea, dry mouth, sickness…nothing. My advice is for your hubby is to accept his oncologist’s recommendation. There are a lot of exciting clinical trials underway in immunotherapy and radiologand therapy just to name a few. Good luck!
Thank you so very much. Just a question, what was your highest PSA? My husband was at 74 today.
Hello,
My highest PSA was at diagnosis 1700. Widespread metastases. Too numerous to count. Bone lesions from my neck to my knees. Gleason 8 (4x4). Fortunately no soft tissue involvement. Scans showed the Prostate Cancer was only in my bones. My urologist told me to put my affairs in order as he thought I only had 6 months to a year left. That was eleven years and two months ago. Lots of drugs, some radiation but no chemotherapy so far. My PSA right now is 0.14.
The SPLASH trial investigating Lutetium pre-chemotherapy was only looking for ten men from British Columbia. I was the tenth and last one chosen. Very lucky! My advice to you is to do your homework, and learn as much as you can about this damn disease. If you are offered a clinical trial that seems worthwhile and might be of some benefit to you, then...volunteer! Hope that helps!
Wow, that is amazing. I just shared your information with my husband and he went from depressed to a smile on his face and hopeful. Thank you
My pleasure,
I was fortunate at the beginning of my journey to meet many knowledgeable people and receive lots of good advice. That proved invaluable. Four things every person with cancer needs. One, a supportive wife, family and friends. Two, knowledgeable and wise medical doctors and oncologists who are at the top of their game and who offer good advice. Three, an inquiring mind so when you come to a fork in the road and have to make a decision you do so with confidence. Four, being open about your disease. Unfortunately, men are frequently the worst sex. Many men simply do not like talking about their disease. I think that is a big mistake. I encourage your husband to join a support group. Princess Margaret hospital in Toronto has a great reputation. One of the best in Canada. You are in good hands. Good luck to both of you.
Thank you once again. My husband, Mel read your comment here twice. You hit home and our hearts. We cannot thank you enough. Is there another support group you would recommend? Hubby is bad with exceptance of this horrible cancer, however he says I'm the best support system he has. I'm happy he thinks that, however I know he needs to hear from so many on this forum as well, for support. I will always be with him forever and a day.
So glad to hear your news, RyderLake2. I’m crossing over from the control group to the active arm of the same study in 2 weeks at Weill Cornell in NY. Very happy to hear you had no salivary gland SE’s.
I would go with the trial .
You are at Princess Margaret one of the top 5 in the WORLD for treatment % research.
Thank you. Looks like this would be the best option right now.
sounds like you and your husband are engaged with excellent care ( Princess Margaret) and a brilliant and caring support group (Malecare). Well done!
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