experiencing stomach-ache side effects

[Jpburns]

I’ve been on Orgovyx since mid-December. Normal SE; fatigue, sweats, brain-fog, etc. May 10th I started adding Abiraterone acetate and Prednisone.

The past week I’ve been experiencing stomach aches, sorta some contstipation (straining) and mild nausea. Any guesses if it’s the newer meds? The info lists stomach pain as a possible SE, but trying to figure out if that’s really what I’m experiencing.

Anyone else on this regimen who can share their experiences?

Thanks in advance.

[JohnInTheMiddle]

May I ask if you take your Prednisone with food? I have a breakfast an hour after the Abiraterone and with the breakfast the prednisone in a few supplements like magnesium and vitamin D etc. (I take my calcium with the Abi.) My ADT is injected Firmagon.

[Jpburns in reply to JohnInTheMiddle]

I have my prednisone in the morning, after breakfast. The Abiraterone is taken in the evening (2 hours after dinner).

[Derf4223]

From Dr. Google -- Drug Interactions between abiraterone and Orgovyx

Drugs.com

drugs.com › Interactions

Let your doctor know if you experience nausea, vomiting, constipation, abdominal cramping, confusion, dizziness, lightheadedness, fainting, muscle weakness, ..

[JohnInTheMiddle in reply to Derf4223]

Huh?

Drug interactions between Abiraterone and Orgovyx

[Jpburns in reply to Derf4223]

yeah, I looked there, but said no interactions. Those may be the side effects of the drugs.

[Psanorma]

Hi, I have been taking those medication and yes I do have those SE. It is pretty common to have those SE.

[Jpburns in reply to Psanorma]

That’s oddly reassuring. Thanks.

[TrashPanda72]

I have gone through the whole range. Last (1st) go around with Lupron and Zytiga, protein shakes helped with the nausea. This go around, went through the nausea phase in about 2 months, and have now hit zero appetite zone…. I do not know which one I preferred.

I make jokes about getting ready for “hot girl summer” (yeah castration!), but the overall lack of hunger is disturbing

[Jpburns in reply to TrashPanda72]

I have NEVER lost my appetite. That would be weird to go through.

[vintage42]

"... on Orgovyx since mid-December. Normal SE; fatigue, sweats, brain-fog, etc. May 10th I started adding Abiraterone acetate and Prednisone. The past week I’ve been experiencing stomach aches, sorta some contstipation (straining) and mild nausea."

I am on Orgovyx since mid-December and Abiraterone/Pred since late February. Some sweats and fog, but no fatigue, and no gastro problems at all. I take 2 heaping teaspoons of Metamucil powder before bedtime. The 10 mg of Prednisone is causing easy hand and forearm skin bruising and tearing.

[SteveTheJ]

Miralax is excellent for hard stools regardless of the cause.