Thoughts on using AI for ADT decisions

[Mgtd]

I found the following article in the NEJM to be interesting. You may want to review it for future reference to help someone in the future making decisions about their cancer treatment or incorporating AI in your research.

Just a side note my grandkids are being exposed to this type of research methodically at the university in various upper level courses.

evidence.nejm.org/doi/full/...

Interesting use of AI in researching medical issues. Any thoughts/experience on using AI in your treatment decision making or research?

[fourputt]

I think this an area that will be extensively researched and hopefully refined to a useable product in the near future. I started my journey in 2012 at age 62 with a prostatectomy and SRT in 2018. I am now experiencing another (relatively slow) PSA rise . I've had a PSMA scan within the last year at PSA of .4 and it was negative. I intend to continue monitoring closely and utilize every radiological remedy if/when it does show up on a scan and is Oligo but at 74 years old I would like to know, given my well documented history, if ADT would actually extend my life expectancy if/when I get to that point. I know there won't be any guarantees but I would gladly pay for a LEGITIMATE AI generated "guess" when I get to that crossroad.

[Worked_the_World]

I have significant reservations about AI without being an expert in the technology. Firstly, how does the algorithm judge between two views that do not agree? Consider that on this forum we have difficulty getting two different physicians to agree on a course of treatment. Secondly, even doctors in agreement often differ on degrees of treatment to offer. Thirdly, selection of courses of treatment are highly nuanced to the person being treated. Yes, I am skeptical.

[maley2711]

With AI and medical, of course you would ask for your trusted MD's opinion about the AI opinion? Just about all treatment strategies have an X% probability of working for Y years......none are predictive of an individual's outcome. Eg, believe I've seen that mono ADT/Lupron extends life aby approx 1-3 yrs....maybe 2 on average. And when you are told you need X months of ADT with your RT treatment, what does that really mean? Well, in actuality, some men would need zero ADT to achieve great RT results......we just don't know which men are in that group? Result is that many men are mucho overtreated ...but which men? let's hope future men will have the benefit of decisive studies!!

[j-o-h-n]

Always remember: G.I.G.O.

Good Luck, Good Health and Good Humor.

j-o-h-n