Hoilday: I started a Zytiga holiday... - Advanced Prostate...

Advanced Prostate Cancer

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gsun profile image
gsun
14 Replies

I started a Zytiga holiday yesterday. Still on Lupron for now. How long should I keep taking prednisone? I know Zytiga clears out pretty fast.

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gsun
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14 Replies
gsun profile image
gsun

How do you taper off from 5mg? Pretty low already.

6357axbz profile image
6357axbz

one every other day for a week then 1/2 every other day for a week

gsun profile image
gsun in reply to 6357axbz

Sounds reasonable.

Mike1971 profile image
Mike1971 in reply to gsun

This how my doctor instructed me to taper of prednisone as well.

45yrsDenmark profile image
45yrsDenmark

I took a quarter off every week...

LongTimeRunning profile image
LongTimeRunning

Wishing you a long and peaceful vacation!

gsun profile image
gsun in reply to LongTimeRunning

Thanks. Been on this trip almost six years.

Proflac profile image
Proflac

Hi. Curious as to why you stopped zytiga while continuing ADT? If u don't mind sharing that is.

gsun profile image
gsun in reply to Proflac

This is step one. Want ot see the effect on my PSA from the Zytiga before dropping the ADT.

jackwfrench profile image
jackwfrench

Eager to hear this as well as I am considering a Zyt vacation. And what is the monitoring plan? I t makes sense to me because Lupron addresses 85% of the testo- Zyt adresses 15% but seems to create most of the side effects for me.

gsun profile image
gsun in reply to jackwfrench

Doing the regular three month blood test first as it would take a while for the PSA to rise. If there is a rise, then once a month.

85745 profile image
85745

I am not sure on your question, but early on in my consult with my oncologist she wanted to put me on Adt and prednisone, so I asked how long would I be on prednisone the reply was the rest of my life, I said ok I'll let you know. I learned for me, I Never refuse anything when in a doctors office I found put on my record . I have a friend who was on high- med-then low dose pred for a few years ...... Maybe I can ask him to let you know his experience sometime in a loud diner over a cup of coffee - Only because he always swears a lot no matter what. Not making any steered or suggesting comments one way or another I am a nobody not a Doctor - Underline my words : I , me, and my , in it's pure form- context here in.

gsun profile image
gsun in reply to 85745

Prednisone is only needed if you take Zytiga. It mimics the cortisol that Zytiga lowers. BTW - I swear a lot too!

Still_in_shock profile image
Still_in_shock in reply to gsun

Effin right

The problem is taking 5 mg at once.

It spiked my blood glucose a lot for the first 8 hours. My previous MO, said, its a replacement dose. Yeah, but 5 mg released throughout the day. Ive been taking 1/4 of that 5mg pill 4 times a day. Helped a lot.

It will make it easy to taper when I stop Z/P in 6 months

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