PSA Rising and MRI Negative

[Inquisitive_one]

My husband PSA has been rising after Prostatectomy. A recent PET Scan showed cancer cells in the Prostate bed, but the MRI didn't pick-up any disease. The Oncologist is checking labs, and will start my husband on HT.Question for the group. Why would PET scan pick-up cancer cells, and not the MRI?

TY

The Inquisitive One

[Tall_Allen]

Because the PET scan is more specific for PCa.

[Walnut987]

I am not a doctor. I have PCa and have had both the MRI and PSMA PET scans.My understanding is that the PSMA PET scan is much more sensitive to prostate cancer cells, while an MRI is showing the organs. MRI is useful for finding tumors on the prostate, seminal vesicles, lymph nodes, and maybe bones, but it's only about 75% accurate and can miss things. The PSMA PET scan will light up any prostate cells anywhere in the body and can find smaller groups of cells.

[Inquisitive_one in reply to Walnut987]

Excellent, I'm an RN and didn't know that. Your explanation is much appreciated.

[dac500]

In 2018 when PET/CT scan showed extensive lymph nodes involvement, MRI came out clean.

[marlins1]

Assuming localize spread only, looks like your husband is a candidate for salvage radiation. Will need a full work-up and discuss with his Oncologist.

[Inquisitive_one in reply to marlins1]

TY, we're working with his oncologist

[j-o-h-n]

How old is your dear Husband.......... I'm nosey too..........

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 01/07/2024 4:09 PM EDT

[Inquisitive_one in reply to j-o-h-n]

J-o-h-nMy husband is going to be 75 this year.

[Inquisitive_one in reply to j-o-h-n]

I'm not sure if this's a duplicate, but my hubby is 75 this year. He's in good health with the exception of the prostate cancer.

[j-o-h-n in reply to Inquisitive_one]

Thank you for your response.

This is what you should give him for his 75 birthday "peace and quiet"....

His 85 birthday: "peace and quiet"....

His 95 birthday: "peace and quiet"...

He will be around to celebrate them (you too)...that's for sure.

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 01/09/2024 5:43 PM EST

[Inquisitive_one in reply to j-o-h-n]

TY for your kind word.I'll focus on your suggestion of less nagging and more "peace and quiet"