ONCT-534

[Lavender22]

Greetings,

Recently I read that the FDA is now fast tracking this new drug— ONCT-534. Apparently it’s meant to follow-up on drugs such as Abiraterone and Xtandi once they have failed.

I’m curious if anyone here is participating in the trial — phase1/2–and if anyone has any information outside of the press release.

Thanks so much,

Elisa

[tango65]

They just started recruitment. The initial cohorts will receive a low dose 40 to 80 mg and the last cohorts 400 to 600 mg. They do not allow to cross over from a low dose to a higher dose. There are not data in humans. Nobody knows if it will work.

[john205]

This is still in early phase trials. Initial results are not expected until sometime in 2024 and then more advanced trials will be needed.

[Lavender22 in reply to john205]

Thanks. I guess we will wait and hope for the best and see the results. Maybe the cure won’t be as bad as the disease;).

[j-o-h-n]

See several posts regarding ONCT-534 in H.U. History file..... also see

ONCT-534 Gains FDA Fast Track Designation in mCRPC

October 27, 2023

Sabrina Serani

from the MaleCare newsletter (found in H.U. History file).

A Happy Christmas to you and to that nice guy with advanced prostate cancer.

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 12/23/2023 1:00 PM EST