Modified Citrus Pectin Treatment in Non-Metastatic Biochemically Relapsed Prostate Cancer: Long-Term Results of a Prospective Phase II Study.
Keizman D, Frenkel M, Peer A, Rosenbaum E, Sarid D, Leibovitch I, Mano R, Yossepowitch O, Wolf I, Geva R, Margel D, Rouvinov K, Stern A, Dresler H, Kushnir I, Eliaz I.
Nutrients. 2023 Aug 11;15(16):3533. doi: 10.3390/nu15163533.
PMID: 37630724 Free PMC article. Clinical Trial.
Thank you for sharing. Do you know of any studies in metastatic CRPC?
No I don't. I have a monthly report sent through Pub Crawl. If I see anything interesting I post it to forum.
Started taking this last month
I took it for about a year and it had no impact. But then I’m metastatic which may have had something to do with its lack of effect.
Thank you for posting! Will be interesting of they dig a lil deeper and discover the mechanism which benefits the PCa patient 
and why/which cell lines are affected or not. Good stuff nonetheless!
I was taking MCP for a while, but got a bit expensive. Any cost effective options to get it in Australia that anyone is aware of?
Taking pectasol for nearly 6 years now.
Hi Niso, my husband is taking PectaSol too. Is your from EcoNugenics? My husband has had two appointments with Dr. Eliaz the formulator. Did you find any significant improvements? My husband is taking it for fibrosis.
Yes it's econugenics 1.5 scoops twice a day on empty stomach.I realy don't know about effectiveness because I do abiraterone + orgovyx+ off label drugs+ supplements aswell.
Did operation and radiation at the beginning.
Psa Was undetectable for long time but now it's slightly rising.
I understand. In the same boat. When and if my husband is healed we will be like it could be this or it could be that… or that or that… or that…. or this…or this…
What's happened with your condition during that period, which is quite long. Can you give us some details on how you were six years ago vs now? Of course, I guess regular treatment would enter the picture as well.
"Patients were given 4.8 g of P-MCP to take orally 3 times per day for the duration of the study." Thats a whole lot of MCP!
I am on my 2nd container of Pecto sol C mcp . I cringe at the price , more than my electric bill, lol. Thinking about cutting back to every other day or 4 days a week? Any thoughts ?
My husband has had two appointments with Dr. Eliaz the formulator. His recommendation was that my husband take 18 capsules per day for fibrosis (cirrhosis). Anything less for my husband would not be a therapeutic amount, per the creator and man you see mentioned on most of the studies.
Thanks, I use the powder mix , Pecta sol is fairly good for detox , and I think kills cancer to a small degree. I am taking so many supps it's crazy. just started taking Rauwolfia V extract another pricey adventure, lol
Yes, the powder is the best way to go. We switched to that after we found out he wasn’t taking enough with what was recommended on the capsule’s bottle. And I know what you mean, my husband has a “basket” of supplements. His Hepatologist recommended he stop ALL supplements so he went off of them for a entire month. His pee started turning dark yellow. His eyes turned yellow. He felt like (insert poop emoji). Two weeks back on his supps and he was out chopping down trees and dragging logs. I think my husband would be dead by now without them. I’d love to know more about about Rauwolfia V extract. Never heard of it. Peace and health to you.
The trial would have been stronger if there was a placebo arm. Hard to know the effects without that.
I took MCP for a year, and trying to decide whether to continue. I noticed Ecogenics provided a grant for the study, and one of the lead scientists is Eilaz, an Ecogenics founder, who's been involved with MCP for two decades, so I'm wondering about the objectiveness of this study.
Dr. Eliaz seems to pop up in every MCP study. He also sells it. I'm not saying it's not useful. I've tried it among 75 others. I know it has its supporters.
Non randomized self selected participants makes it fatally flawed from selection bias and perhaps also some healthy user bias.
Early progression per PSA dynamics is not linear but varies. Those with more aggressive PSADT are more likely to seek out and participate. Then there is always regression to the mean. The worst get improved and the best get worse. Not a treatment effect but just statistical variability. Some skepticism is warranted. But no harm in trying it if you can afford it. MB
Would the posters who have taken it post the price?
When Tall Allen doesn't weigh in, I always think it's because he believes it's BS and doesn't bother to respond and cause a ruckus. Don't want to put words in his mouth though, and I certainly value his learned opinion. His absence concerns me.
What is there to say, it's only a study from a government sponsored website.
I was going to take the stuff until I realized that you have to ingest it in any orifice of you body...
Good Luck, Good Health and Good Humor.
j-o-h-n Wednesday 09/06/2023 3:35 PM DST
I have been taking the EcoNugenics brand MCP for 15 years. There were many studies years ago that showed the MCP group PSADT was considerably longer than the placebo group. The theory is that cancer cells are floating around in our blood looking for a place to attach and form a tumor. The cancer cells are sticky to bones, organs, and each other using something called galectin3. The MCP seems to coat the cells inhibiting the gal3 to prevent the cells from being sticky. If the cells do not stick to anything, they float harmlessly in the blood until they die. That's the theory as best I remember the explanation.
Thank you for sharing this.
Yeah i tried it a few years ago when i was working but it's just too expensive, think it's worth having a go, it's natural, it has potential to help, like others have said its good for detoxing and that's important, it's just to expensive.
I see threads on here from years ago about citrus pectin. I'm surprised more people have not chimed in recently that started taking it early on in their disease and can attest to its effectiveness as far as preventing metastasis many years later.
Just because the study is on a government site doesn't mean that it's a source of reliable information. The study referenced is relatively short-term only 18 months total, a very small sample of cancer patients, and as others have pointed out it's not an RCT, has no placebo arm, and was sponsored by the manufacturer of pectasol. Couple that with the study about PSADT variability and in my opinion the study is worthless.
You really need to run a trial with this on at least a couple hundred people with a placebo arm and have those people be at the very early stage of biochemical recurrence and monitor them for probably 10 years to see if they develop metastatic spread or not.
Assuming many of these substances are safe for advanced prostate cancer patients just because they're natural and have a smattering of studies showing beneficial effect on PSA is very presumptive because it is widely known that at some point in the Cancer's progression any substance that has strong antioxidant properties or upregulates nrf2 can actually help cancer survive and grow.
But as has been pointed out there really isn't enough funding to do large high-powered studies over very long terms for many of these natural substances because they cannot be patented.
The bottom line is there's no silver bullet for a lot of diseases, yet the nutraceutical market is making billions off of desperate people looking for that natural silver bullet.
I don't say this to discourage anyone from doing extensive homework and trying to understand biochemical processes and how they relate to their disease and the various supplements available and thereby try to make an educated decision on what they want to try.
Modified citrus pectin
Modified Citrus Pectin
Modified citrus pectin and cimetidine 
Modified Fruit Pectin
