Clinical trials for ATM gene

[mysticmini]

Have ATM gene and castrate resistant. Stage 4b lymph nodes spread. Anyone have any luck with any clinical trials for ATM gene? Have already had chemo and failed Zytiga.

[Tall_Allen]

Although Lynparza (olaparib) is indicated for ATM+, it actually has little effect.

There is a BAT trial at the VA:

clinicaltrials.gov/ct2/show...

And this trial has an ATR inhibitor in addition to a PARP inhibitor:

clinicaltrials.gov/ct2/show...

[mysticmini in reply to Tall_Allen]

Thank you!