Lupron has side effects like CVD, brain fog, and loss of sex drive because it wipes out T production. Also because of castrate T, DHT is usually not a problem. Casodex has fewer side effects because T is not lowered but DHT is still a problem. I just read a study where Casodex + Avodart was just as effective as Lupron in controlling PCa. So, why take Lupron when you can take Casodex + Avodart and lessen so many of the side effects of Lupron therapy.