I recently had a Guardant360 CDx liquid biopsy that showed my BRCA2 inherited mutation, previously treated with Olaparib successfully for two years, is now classified as a reversion mutation. Prior to finding out this result, I had hoped that I could re challenge the use of Olaparib. Unfortunately, this is no longer an option.
Has anyone experienced a reversion mutation, and how did it affect your treatment(s)?