radium 223

[tonmead]

I am 6 years into stage 4 prostate cancer. Have had SOC treatment in UK. Best PSA was 0.08 about 2 years ago. Since then have had bicalutimide, enzalutimide some localised radiotherapy for back pain. Also been on cabazitaxel, which eventually failed. I am now into my 2nd. treatment of radium 223. So far I have experienced the pain flair but very little pain relief which is why im going through this treatment. Can anyone who has had Radium 223 pass on their experience. I have 4 treatments to go, wondering if its worth it.

[Tall_Allen]

Some patients get good pain relief from mitoxantrone (an older chemo drug).

[Shooter1]

If it works, it is worth it. 3 treatments for me for me. #4 canceled when scans showed 4 new mets after 3 months.... Best of luck to you with your treatments... I never had pain increase and it was gone by #2.

[NotAlwaysSunshine in reply to Shooter1]

My husband was the same. Only 3 treatments.

[Shooter1 in reply to NotAlwaysSunshine]

Sorry to hear he also didn't benefit. Works for some, not for others... Best of luck.

[Mcrpca in reply to Shooter1]

Did you have any nausea/vomiting/diarrhea from the Radium 223? If so, how soon after injection did side effects start? I’m just getting ready to start and treatment center is a 5 hour drive. Thanks

[Seasid]

Are you on bone strengthening medication?