"Why Conventional Wisdom About Cancer Can Be Misleading", general and thought provoking.

[FRTHBST]

Came across an interesting observation in an excerpt from a recent book by an evolutionary biologist. A bit general , still might be worth a read-lithub.com/why-conventional...

"On the contrary, taking cancer cells from a tumor microenvironment and implanting them in a normal cellular environment tends to halt their growth, and often promotes programmed cell death."

The author briefly discusses relationship of genetic mutation and larger cellular processes. He proposes the Krebs cycle as a likely center in what drives cancer. This direction of thought suggests that along with what are the best wrenches in our known toolbox for dealing with cancer, there may be very good reasons to expect that the current metabolic studies (Quercitin and Radiation therapy in PCa , "Targeting the radiation-induced ARv7-mediated circNHS/miR-512-5p/XRCC5 signaling with Quercetin increases prostate cancer radiosensitivity" jeccr.biomedcentral.com/art..., is but one example.) will generate designs for tools to fit nuts and bolts we haven't yet begun to imagine.

[MateoBeach]

Nick Lane in this, his most recent book, Transformers. Highly recommended if you are at least basically familiar with intro level biochemistry. I’m currently enjoying the Audiobook version but haven’t gotten to the later sections on cancer yet. He also has a good interview summarizing the theme in the Podcast “Mindscape” with the physicist/philosopher Sean Carroll.

Lanes’ previous book Oxygen, the Molecule that Made the World, is one of my all-time favorite science books and does not require biochemistry 101 to follow.

[Scout4answers]

Interesting piece of out of box thinking.

[Magnus1964]

Nice article, thanks for sharing.