"
They revealed that the inactivation of AR by CRISPR/Cas9 technology successfully inhibited the prostate tumor cell size by inhibiting cell proliferation and promoting apoptosis. Hence, it is suggested that CRISPR/Cas9 could be a revolutionary and potential technique against prostate tumors in the upcoming time [76]. Similarly, Ye et al. [77] demonstrated that the lentiviral delivery of CRISPR/Cas9 into the human xenograft mouse model (PC-3) significantly inactivated the GPRC6A receptor. They suggested that the knockout of the GPRC6A receptor by CRISPR/Cas9 might be resulted in reducing the prostate cancer cell size by inhibiting the mitigation and cell proliferation.
"
ncbi.nlm.nih.gov/pmc/articl....
Anyone following this? A ray of hope?