is CRISPR promising for prostate can... - Advanced Prostate...

Advanced Prostate Cancer

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is CRISPR promising for prostate cancer?

Soumen79 profile image
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"

They revealed that the inactivation of AR by CRISPR/Cas9 technology successfully inhibited the prostate tumor cell size by inhibiting cell proliferation and promoting apoptosis. Hence, it is suggested that CRISPR/Cas9 could be a revolutionary and potential technique against prostate tumors in the upcoming time [76]. Similarly, Ye et al. [77] demonstrated that the lentiviral delivery of CRISPR/Cas9 into the human xenograft mouse model (PC-3) significantly inactivated the GPRC6A receptor. They suggested that the knockout of the GPRC6A receptor by CRISPR/Cas9 might be resulted in reducing the prostate cancer cell size by inhibiting the mitigation and cell proliferation.

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ncbi.nlm.nih.gov/pmc/articl....

Anyone following this? A ray of hope?

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Soumen79
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Seasid profile image
Seasid

I think no. It was only a mouse model? I wouldn't volunteering for that RCT. Hope that others have a better understanding than me.

Soumen79 profile image
Soumen79 in reply to Seasid

Thank you so much for having a look at it!

Scout4answers profile image
Scout4answers

The cure is likely to come from a novel approach such as crispr

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