Are there statins that extend mortality if taken with ADT in advanced metastatic pica?
Statins and ADT: Are there statins that... - Advanced Prostate...
Advanced Prostate Cancer
Not that anyone knows of. All data is retrospective and not worth the paper it is printed on to patients.
Inflammation and PSA have been known to run together. Climbing PSA, you many times find climbing Inflammation in Blood Tests. And the reverse appears equally so. So less inflammation is good for the body. Anything good for the body is a plus for your overall health.But, there is no evidence that Statins will extend your Mortality.
There are a number of articles/papers--->Statins and Pca at Pub Med. If you can, and have the time try to read a few.
There are dozens of research articles available about statins and PCa. Statins delay progression by slowing epithelial mesenchymal transition which is first step in formation of mets. Some studies say that statins can delay castration resistance. If some one has high cholesterol and Pca then statins are very useful for both heart and prostate. Dr Myers has been a proponent of statin use and so has been Dr Mark Sholtz.
I was taking statins until now, but I stopped just now. I want to take a drug holiday. I will see how will it go. I want to see my real PSA and statins can reduce it. I am hoping that I will feel better without unnecessary medication. I will monitor my cholesterol levels. Hope they will stay in a normal range.
Correlation or causation or a healthy user bias (more visits to doctor and monitoring blood parameters more frequently)? My PCP and my urologist feel that statins might be beneficial for PCa.
Speculation that statins lower intracellular testosterone: healio.com/news/endocrinolo...
My medical oncologist also said that statins lower not just the PSA, but also the cancer. It removes by the cancer horded cholesterol so the cancer will not have a fuel to produce testosterone when it mutates to independently produce testosterone from by the PC accomulayted cholesterol.
Why don't you have a MO? We all here believe that we should have one. Urologists are surgeons. You should move to the medical oncologist as soon as possible.
I have an MO. I haven't talked to him about this.
Good info that your MO also thinks statins are beneficial. Thanks.
I went on a statin while on no other treatment. My PSA dropped dramatically. Unfortunately, I could not tolerate the side effects of the statin.
Yep, some suffer statins effects more than others. I assume you tried different statins.
After my experience with atorvastatin (pain, depression, suicidal), I told my cardiologist, no statins. I'm on zetia.
The side effects you had with statin are really very uncommon. Most people just have some muscle aches esp in legs. I had these aches when I took 20 mg Atorvastatin.. but after lowering the dose to 10 mg a day..those aches disappeared.
When I had to go on a statin, I was taking Xtandi and found a research paper that recommended simvastatin as working well with Xtandi. As I had already had a bad reaction to Lipitor I started this old statin and it works great on the lipids (pharmacists do freak out at my using this old drug instead of an expensive new on). On the cancer, who knows, as mine has progressed in the past few months and I no longer take Xtandi. But my lipids are now great!
Would you please be kind enough to tell us your bio. Age? Location? When Treatment(s)? Treatment center(s)? Scores Psa/Gleason? Medications? Doctor's name(s)?
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Good Luck, Good Health and Good Humor.
j-o-h-n Sunday 06/19/2022 9:47 PM DST
I’ve tried them all…currently on lovastatin and seem to be tolerating it well. My MO encouraged me to get back on them…and a recent CT scan showed early plaque buildup so I have to step it up…don’t want any CV issues doing me in!