Lynparza Failing?

[Newyork6264]

My Psa has gone from 40 to 50 over past three months. However, my scans show very little progression. My onc and I are trying to decide if due to the scans we continue on Lynparza for a while. My other option is going back to chemo. Any thoughts. Should scans override PSA increase.

[tango65]

In general, change in treatment are decided when there is radiological evidence of disease progression.

[Tall_Allen]

If you can tolerate Lynparza longer, consider combining with a radiopharmaceutical (Xofigo or Pluvicto):

ejcancer.com/article/S0959-...

clinicaltrials.gov/ct2/show...

[NotAlwaysSunshine]

My husband's MO told us that he would keep him on Lynparza for a while. PSA in January was 260. It's 16.8 now. The last 4 weeks PSA only came down 1 digit. Scans are mid June. Fingers crossed to ride this train as long as possible. Take what we can get right now. Blood work is decent.