My father started the journey last year with a PSA of 6491 and dropped to 0.79 as of December of 2021 as of two days ago his PSA was 0.74. He is taking eligard every 6 months, no other meds . His initial MRI showed 2 prostate tumors and enlarged pelvic lymph nodes. My question is should he start Zytiga or Xtandi to lower his PSA more?
He is still using the cather and lately has developed bladder spasms and was described oxybutinin but after a few days he developed low blood. He is already on lisinopril and amlodipone also on short term urobel. Should he stop oxybutonin? I am trying to make an appointment with his primary doctor .
Written by
naples2021
To view profiles and participate in discussions please or .
Yes, that is a common side effect of oxybutynin. Hopefully, he won't feel light-headed once his body gets used to it. His doctor may want to cut down on his BP meds if he knows he is taking oxybutynin. Incidentally, it is being investigated for relief of hot flashes- has he noticed they've diminished since he started taking it?
I assume radiation was not recommended because he is already suffering from lower urinary tract symptoms.
He should certainly be taking abiraterone as in this trial:
As always thank you Tall_Allen, he has experienced hot flushes only a few days after eligard has been administered. I will talk to his oncologist about Zytiga next week.
Oxybutynin (Ditropan) is a anticholinergic drug used to reduce urinary urgency. It does not cause low blood pressure, to the contrary it may increase the blood pressure.
It is not an alpha blocker like the other drugs used to improve urinary flow in prostatic hyperplasia. These drugs may cause hypotension.
This is the information of the FDA:
"DITROPAN may aggravate the symptoms of hyperthyroidism, coronary heart
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
PSA stable but Cancer spread to liver
Same story as last 3wk checkup! Alk Phos decreasing and PSA considered stable 
with drawl side effects or new side effects 
Xtandi stomach side effects
