Sadly it looks like after roughly 9 months of Nubeqa as a monotherapy, the Nubeqa alone is not going to keep PSA at bay. PSA has steadily crept up from a low of .9 to 2.6 today. Ct scan showed that the size of the largest lymph node tumors had been greatly reduced, but there are more of them (not sure if thats good or bad). I am going to try adding Relugilix to the Nubeqa to see if taking testosterone back to castrate levels has any effect. My Uro thinks it will lower it some, but no telling for how long since I am castrate resistant. Hoping that the Relugilix does not cause the nasty heart and cognitive SEs I experienced previously while on Firmagon and Xtandi, but if it does, it sounds like things return to normal fairly quickly upon stopping. Depending on how well ADT + Nubeqa works, my next choice is going to be LU177 treatment.
Nubeqa monotherapy experiment coming ... - Advanced Prostate...
Nubeqa monotherapy experiment coming to end
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joeguy
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Good decision!
I thought these next gen anti-androgens would be so effective that you would not need to add Lupron. However, I read a few small studies now, which indicated that this is not the case.
My husband has been using Nubeqa with abiraterone and at first dropped his PSA by 100+ points. It has since stabilized.
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