Can PSA be determined from the blood clots that are produced in from radiation cystitis?

[Lyubov]

Hubs had RARP 2014; IMRT & ADT 2016 for recurrence. He's now experiencing low but increasing (doubling) PSA. Simultaneously, having second bout of radiation cystitis, using Foley to dilate urethra. But blood clots are being produced. Just wondering if that sloughed off tissue (from bladder/urethra) could be biopsied for PCa?

[Tall_Allen]

PSA is in the serum. As for PCa, it is unlikely that they will find any in the blood clots and sloughed benign tissue.

[Lyubov in reply to Tall_Allen]

Thank you, TA! Clearly, I don't understand. So it's benign areas damaged by the radiation that don't completely heal. . .

[Tall_Allen in reply to Lyubov]

scar tissue, yes.

[Lyubov in reply to Tall_Allen]

It's the cancer beast. But this side-effect we didn't expect at all, not really stressed when the IMRT + ADT administered. He struggled terribly with the ADT side-effects, so this comes as a delayed "bonus." I do appreciate your clarifications. Thank you!

[tango65]

Since he has a prostatectomy, the prostatic urethra is gone, I doubt any PC could be present in the blood clots or tissue coming from the bladder.

[Lyubov in reply to tango65]

Thanks so much.

[tango65 in reply to Lyubov]

Best of luck!!