Stage 4 Metastatic Prostate Cancer

Stopped pee ability. Got foley catheter. Found prostate cancer in lungs, lymph, liver, sacrum, urethra, penis. Hormone therapy worked for a while. Then zytega did nothing. Then Taxatare (Docetaxol)' now Jetana (cabazitaxol). Last PET scan, looked pretty godd, two small places left. PSA NEVER MOVED.

Screen at age 50, do not wait!!

11 Replies

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  • Also, Gleason 10 on both sides of prostate.

  • Howdy D3dcs2,

    Wow. Lots of treatments already. How's it been going, lately?

    Charles

  • Holding my breath for this chemo to work. Praying

  • D3dc,

    When cancer is everywhere we are nowhere! But still there is light and hope for life. Cling on to a resolute determination that you will live until the next effective treatment is available for your salvage. I started my journey only in 2015 and my pathology is too much favourable to offer you any advice. But we have veterans in this group with tough battle experience who will definitely help you to address your issues however serious they are. Thank you for joining us.

    Sisira

  • Has your Med Onc ordered a liquid biopsy? The Guardant360 test requires only 2 tubes of blood and it will determine if your cancer has genetic defects. Mine did and Dr. Myers prescribed Lynparza (a PARP inhibitor) which stops cancer duplication at the DNA level. Could buy you more time.

    Never Give In.

  • Dr Myers also has me on Guardant-excellent test, highly recommended also

  • So sorry. Keep fighting. Would Lupron be an option? Also, some recent studies have shown that using a mixture of ADT's together can have positive results. To that end I am now on a mixture of Lupron and Zytiga.

    Please know we are all pulling for you!

    Good comment on getting screened at 50. It hits close to home for me. With your permission I would like to expand. Do not rely solely on tests. Even if you are getting digital and PSA tests consider going to an urologist if you have ANY symptoms of an enlarged prostate. I had digital exams since I was 40, PSA since I was 50. Around 53 I started to have some symptoms of an enlarged prostate. Doctor stated it was normal and not to worry since my tests were fine. She stated that there was no need to see an urologist. Then at 58 the tests finally indicated something was going on. Turned out I had advanced cancer that had spread. If I saw an urologist at 53 then perhaps it could of been caught before it was advanced.

  • Excellent comment, I have a similar experience, normal DRE and PSA , but even though I didn't understand yet much about PSA, something about PSA trend bothered me. I was chicken to take biopsy, asked my dr , he said there was no problem. I pushed for biopsy, finally sent me to urologist-it was G4+3.

  • Yes...I agree...see if genetically driven because you might be candidate for Lympraza or other parp inhibitor OR new immune drugs like Ketruda. Look up both those drugs as used in advanced prostate cancer. Also check out PCF website if u haven't already.🙏🏻

  • Foundation One is another source, for Gene Mapping. Defines which mutations you have and then defines what drugs are currently available or in Clinical Trial against your specific mutation. There are 2 new PARP inhibitors, just approved in April, My Oncologist at the Levine Institute, of Cancer, who I was with this week, said one of them, though very experimental, used in men of a pretty dire straight, 90 % received a remission. It was done in a clinical trial situation--I did not ask for details. He also said, there is a Drug company research rush, to come up with these targeted drugs, as they all smell the money. There might be some help from a natural substance, But I cannot suggest, as I am not a Doctor. And it is only available from a foreign country. So there are things around---you need to be in a Cancer Institute of Excellence--Like MD Anderson, or John Hopkins, or Mayo, Or Sloan Memorial, or mine the Levine Cancer Institute, in Charlotte. N.C.

    Sorry you are where you are. I have just offered my prayers, that something will be found.

    Nalakrats

  • A treatment that is becoming more prevalent in Germany and in Australia is theranostics. It involves an injection of Lutetium -177 which is bound to a protein that searches out the PSMA receptors on all PCa cells in the body. The radiation over a course of injections (every 8 weeks) "kills" the cancer cells, but has no impact on normal cells. The half-life of the Lutetium -177 is around 5 days.

    Three drawbacks: About US$7K each injection (2 to 6 required); doesn't work on those men without PSMA receptors (about 10% of men); apparently only available in Europe and Australia to date. Clinical trials ongoing in a number of countries.

    More details at my free ProstateTalk Newsletter at docs.wixstatic.com/ugd/ecc7...

    Results are worth people investigating this treatment (which my brother is undergoing in Sydney, Australia).

    Cheers.

    Alan Lawrenson (Author of An ABC of Prostate Cancer Today - Amazon bestseller)

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