Orgovyx after surgery?

[Hawaii2021]

Husband on orgovyx for 3 months. Finished 28 proton treatments 3 weeks ago. Had lung surgery to remove unrelated cancerous spot. Dr. wants him off orgovyx 2 more weeks. Thoughts? Husband doesn’t want testosterone to rise.

[Horse12888]

This is a first. Doctor wants patient off ADT, patient wants to stay on.

ADT drugs are highly toxic; they harm the body in many different ways, some perceptible, others not.

This is like wanting to do additional and unneeded rounds of chemo.

[Tall_Allen]

Does he have advanced prostatee cancer (T4, N1, or M1)?

[Hawaii2021 in reply to Tall_Allen]

Can’t find the Dr. notes rights now, but stage 3B. Found this: cT2c by exam but cT3b radiographically. Need more info?

[Tall_Allen in reply to Hawaii2021]

So he never had advanced prostate cancer. For his high risk prostate cancer, he should have 18 months of Orgovyx. I hope he had his pelvic lymph nodes treated along with his prostate.

[Hawaii2021 in reply to Tall_Allen]

Thanks! Yes, 18 months of orgovyx is the plan. My husband just didn’t like the idea of being off it for 2 weeks in the middle of his treatment. He’s also become almost total plant-based and researching supplements (not miracle ones😉) Hard to find researched nutrition info specifically for prostate cancer.

[Tall_Allen in reply to Hawaii2021]

I agree- bad idea to stop in the middle - it can select for resistant strains. What is rationale for stopping?

I think the diet and supplements may give you a psychological boost, but there is no reliable data that any of it is beneficial.

[Hawaii2021 in reply to Tall_Allen]

No specific reason for stopping orgovyx from surgeon. Husband talking to MO and will resume in 3 days. Thanks for your help! Value your opinion.

[Tall_Allen in reply to Hawaii2021]

I don't understand why he is listening to a surgeon. He should resume Orgovyx immediately.

[Hawaii2021 in reply to Tall_Allen]

The surgeon communicated with the MO and MO agreed but husband is communicating with MO directly and will resume orgovyx this week. He will have been off 1 week. Was just curious if anyone else was recommended to stop drug because of surgery. Appreciate your input.

[Tall_Allen in reply to Hawaii2021]

This is the lung surgeon?? I've known several guys on ADT who've had surgery. They healed just fine.