Lu-177

[Hillwalker87]

Hi everyone. Is anybody able to suggest anywhere globally where you can receive Lu-177 at the most reduced cost possible? Dad has been told his chemo doesn't appear to be working and his PSA is rocketing at the moment. Many thanks in advance

[Tall_Allen]

Are you in the US? You can check these out:

prostatecancer.news/2020/08...

[Hillwalker87 in reply to Tall_Allen]

Thanks TA. No we are UK unfortunately

[Tall_Allen in reply to Hillwalker87]

The Th-227 trial is at the Royal Marsden.

[Hillwalker87 in reply to Tall_Allen]

Cheers TA!

[tango65]

There are clinical trials in the USA for Lu 177 PSMA and other radioactive metals:

clinicaltrials.gov/ct2/resu...

clinicaltrials.gov/ct2/resu...

clinicaltrials.gov/ct2/resu...

My understanding is that one of the least expensive places abroad to have Lu 177 PSMA treatment is in India.

fortishealthcare.com/doctor...

[tennis4life in reply to tango65]

This is correct.

[Hillwalker87 in reply to tango65]

That's great, thank you very much

[tango65 in reply to Hillwalker87]

Best of luck!!

[Hidden]

India. There are some posts on here about it. Trials work too if you can get in

[Hillwalker87 in reply to Hidden]

Thank you

[ARIES29]

Yes India is cheapest then Singapore I think. Also here in Australia.

[Hillwalker87 in reply to ARIES29]

Thank you

[Eugmn]

I am currently in India now getting my first treatment. Treatment and all scans came to about 6600.00

[Big_Mcc in reply to Eugmn]

Can you give details pls? Hospital and contact name. Was there no visa problems due to covid? Did you arrange your own flights and accommodation? Can you recommend a place to stay near the hospital? Thku

[RCOG2000 in reply to Big_Mcc]

Write to the web address above. (Fortis) and they will reply with all info promptly

[Big_Mcc in reply to RCOG2000]

Many thanks. Very much appreciated. I wish you the best on your journey.

[Chubby42 in reply to Eugmn]

Is that per treatment cost or the overall total cost.

[Eugmn in reply to Chubby42]

Per treatment

[Chubby42 in reply to Eugmn]

Thanks Eugmn I thought it was too cheap for total, let us know how you go after all your treatments & experience at this hospital.

Cheers

Gary

[Eugmn]

I am at Fortis Memorial Research Institute in Gurugram India. It’s about 30 minutes from the New Delhi airport. Dr Ishita Sen.

I don’t have the phone or the email to Dr. Ishita with me at the moment. I believe it has been posted on this site. Let me know if you can’t find it and I will get it to you once I arrive home tomorrow.

We set up our own airfare and accommodations. They recommend that you arrive here on a Saturday evening, use all day Sunday to recover from the flight. I did all of my preliminary scans and Lou 177 treatment on Monday.. We are now departing back to the United States on Thursday evening.Many folks stay at the Westin hotel. We chose to stay at the Taj city center. It made going back and forth to the hospital very easy. All we had to do is exit the back gate of the hotel turn left. Less than a five minute walk and we were at the hospital.

The hospital Set up a service to meet us at the airport when we arrived. There was a gentleman there with a cardboard sign with our name on it and he guided us all the way through the airport and put us in a prepaid cab to our hotel.

[Hidden in reply to Eugmn]

Do you, can you receive LU177 if you have already had Xofigo? Studies in the US say you can not. Thanks.

[monte1111 in reply to Hidden]

Believe TA said the no no on Xofigo was for clinical trials. Don't want to put words in his mouth. Maybe he'll chime in. So I think short answer is yes. Believe me, if I'm wrong, someone will let us know. FDA approval next year?

[tango65 in reply to Hidden]

Lu 177 PSMA treatment is possible after receiving Xofigo treatment.

targetedonc.com/view/177lu-...

[Hillwalker87 in reply to Eugmn]

Thank you for sharing your experience and the best of luck to you

[Twig4]

Thank you for the wonderful info.

[GregHouston]

Here's the contact info and website info for Fortis Memorial. nuclearmedicinetherapy.in Mr. Manav Sadhwani is the hospital's patient coordinator for Dr. Ishita Sen. His email address is [e-mail] or [e-mail] . I just finished up my third treatment at Fortis in August.

[keepinon in reply to GregHouston]

Greg. Just read your profile. What is your PSA after your 3rd treatment? What is your ongoing plan? Best wishes!

[GregHouston in reply to keepinon]

PSA count is currently around 2.4 to 2.9. Dr. Sen said to monitor the count and if it remains low, do nothing for now. However, if that were to change, she said to consider getting another PSMA scan to see what is causing the increase. My last scans did not show any prostate lesions or lymph node issues. But as we know, it only takes a few nasty cells to start a problem.

[Hillwalker87 in reply to GregHouston]

Thanks for all your info Greg

[Bangkok]

The scariest covid countries are the most inexpensive. The Phillipines is around $9,000 per treatment I've been told.

[Misanthrope12]

Sheba Hospital in Tel Aviv. Three treatments at $9,000.00 per not including housing. The treatments are administered every 3 or 4 weeks.

[Gemlin_]

Docrates Cancer Center HELSINKI FINLAND

docrates.com/en/treatments/...

[Hillwalker87 in reply to Gemlin_]

Thank you!

[Javelin18]

There is a managed access program to give the treatment free of charge for patients that meet the inclusion criteria. Search clinicaltrials.gov for trial number NCT04825652.

I am working with UCLA to get into this program, but still waiting for a PSMA PET scan to confirm my cancer is PSMA avid. I also have a friend that is going to Nebraska to receive this.

I recall that MD Anderson and Tulane were also participating, but can't find the references. Dang therapy induced brain fog.

[Hillwalker87 in reply to Javelin18]

The best of luck to you

[yeatz in reply to Javelin18]

Can get it locally, without travel. See my report on FDA requirements. They WANT people to use this service.

[yeatz]

Under U.S. law, patients can use the FDA's "expanded access" (also called "compassionate use") program to get treatment for drugs that aren't approved by FDA. The FDA's website says that 99 per cent of requests under this program are granted. In an emergency, your doctor can get authorization over the phone, and turn in the paperwork later. The FDA wants people to use this program. So you don't have to leave the U.S. to get treatment.

For more info, google FDA's website for "expanded access."

The FDA often gets requests for drugs that are still in trials. Lu-177 has finished its

Phase III trial, and is simply waiting for official FDA approval. (I'm told that the only

problem in getting it here is shipping. This stuff is radioactive, and it takes a little

longer to get it to your doctor.

I've researched this because my doc is considering Lu-177 for me. Hope this helps.

yeatz

[Hillwalker87 in reply to yeatz]

The best of luck to you

[Javelin18 in reply to yeatz]

Thanks Yeatz, I was trying to point out to the group that it was available free here in the US, but perhaps I was not clear in the way I wrote the post. I am getting it at UCLA, since that is where I am being treated.

I gave a second shot at explaining the program in the answer to your following post. I'm guessing that the FDA only acts in a regulatory capacity in approving the expanded access, and the actual distribution under expanded access rules would be handled by the drub company. That is why I posted about the Novartis managed access program.

If there is a different mechanism, perhaps you can explain it. UCLA has the program in place, so I didn't have to contact either the FDA or Novartis.

[yeatz]

Just looked it up; the website for "expanded access" program is:

fda.gov/news-events/expande....

[Javelin18 in reply to yeatz]

I posted above about the Managed Access program run by Novartis. Managed Access is they're catch all term for Expanded Access, Compassionate Access, Early Access, etc. They use that term, since each country has a different name for receiving a treatment prior to regulatory approval.

Here is the link for the description on clinicaltrials.gov clinicaltrials.gov/ct2/show... .

The listing describes the inclusion criteria. In a nutshell, it is progressive mCRPC with prior treatment of at least one taxane drug, at least one NAAD (enzalutamide or aberaterone) and PSMA positive cancer verified with a PSMA PET scan. More specific details are in the clinical trials listing. The contact information listed there is: Novartis Pharmaceuticals 1-888-669-6682 [e-mail] .

I'm getting my PSMA PET on October 15, and was planning to pay the $3300 out of pocket. However, Medicare is covering PSMA PET scans at UCLA and UCSF starting October 1. I'm going to check with the radiation oncology department in a few days to see if Blue Cross Blue Shield will now cover the scan. I don't know if medicare is covering the newly approved PSMA PET scan tracer.