Fasting before docetaxel

[davebliz]

Back in 2019, Dr. Tanya Dorff was involved in a clinical trial where the person fasted for 48 hours before getting docetaxel. The trial was not over at that time. Does anyone know the final results from the trial, any links? Thanks.

[GP24]

I think the trial is still ongoing, she mentions it in this interview: grandroundsinurology.com/dr...

[dockam]

Hi, back in 2015 at the PCa diagnosis, I read about Dr. Valter Longo and Dr. Tanya Dorff conducting research about fasting prior to chemo to lessen the side effects. I did a two day fast prior to each of 15 Taxotere sessions (9 over the CHAARTED protocol) in 2015 and then again with a 6 Taxotere rechallenge ending in April 2021.I had very few side effects from the chemos, mostly hair loss, a bit of metallic taste, and some neuropathy.

In my case, the fasting appeared to have helped. Btw, I still do a 16 hour fast from 9pm to 1pm the next day

osher.ucsf.edu/patient-care...

Fight on Brother

Randy

[Lieto55 in reply to dockam]

Hi dockam - do I understand that you do the 16 hour fast continuously? I've gotten up to a steady-state 14 hours, and it really works to kick up the metabolism. I know I'll remember your words here. Dale Bredesen's book on Alzheimers was where I picked up the habit. Good on you. Thanks!

[dockam in reply to Lieto55]

Yes, with black coffee and homemade veggies, curry, broth until break fast

[Jac_J]

I just did cycle 3 of Docetaxel 2 days ago. I feel ok. No hair loss because of cold cap during treatment, no nausea, just general tiredness (from liver toxicity). No peripheral neuropathy. No change in taste as I suck ice during the treatment.

I do have elevated ALT and AST levels which indicate liver toxicity. This led to a 10% reduction in dosage in cycle 3.

I do not reduce food intake at all before chemo and even increase slightly before hand if I cant eat for 5 hours. Now, if you did what I did, your outcomes may be totally different.

The interesting thing about oncology is they dont actually know what will happen to YOU during the treatment. They will acknowledge that if you pursue it. There are a range of side effects, but it's close to impossible to predict if you will be afflicted. The evidence based studies will give you a range of statistical possibilities but no assurance if it will affect you. There is an element of trial and error.