Considering Reclast

[Parscore]

I done some of the research as best I can. My question is directed to those that have taken Reclast and what your reaction was to the drug. Would appreciate your input on using this drug.

[Tall_Allen]

No need to take it if you don't have osteoporosis.

[MateoBeach in reply to Tall_Allen]

There is another reason to consider it in APC, at least it seems so with denosumab. And might be applicable to zolendronic acid: altering bone micro environment to possibly make it less vulnerable to bone mets.

ncbi.nlm.nih.gov/pmc/articl...

[MateoBeach in reply to MateoBeach]

And yes , must balance risk of ONJ. Dental health status considered.

[Pleroma]

I took an annual dose of Reclast and got about a 3% improvement in my bone density.

ADT after 18 months had pushed me into Osteopenia - the precursor to osteoporosis.

I think I felt a bit "off" for the next day after the infusion. All good. I have taken it two years in a row now. Waiting to see what my next bone density scan will show.

[thudson1965]

I took Reclast in 2019 and 2020 for Osteopenia before I knew I had prostate cancer. It increased my bone density and I skipped 2021 at my endocrinologist advice.

It was a simple 30 minute infusion. I did not have any side effects (again before prostate cancer.

[Woodstock82]

I had one infusion of Reclast. Felt fine at first, but about 6 hours later I had serious chills. Teeth-chattering, body-shaking chills. Oral temperature was 97F. I took some acetaminophen, had a long hot steamy shower, then went to bed under all my blankets. About four hours later I woke up sweating and feverish. Oral temperature was 100F. I drank a pint of water, took some ibuprofen, stripped down, and went back to bed without the blankets. When I woke up in the morning, I felt fine and my temperature was back to normal.

My bone density on the next scan had dropped a little. Perhaps it dropped less than it might have if I hadn't taken the Reclast? No way to know.

Six months later, I had a shot of Prolia instead. Bone density is still dropping slowly, but at least I didn't have to deal with chills or fever.

[Parscore]

Thank you to all that responded to my request for information on Reclast.

[kmksally]

Hi, I thought I'd add my very recent experience with Reclast. I debated a long time and did a lot of research before deciding to get my first infusion. I got the infusion 8/23/21, 2 days ago. The next day I woke up with a terrific headache that dissapated over the day. The rest of the day was pretty rough. I had an extremely quesy stomach, chills and odd feelings in various parts of my body that came and went, similar to the feeling of arthritis.That night after the chills I felt like I had a fever and sweated it out. This morning I woke up feeling 90% better.From other stories I think it could have been worse. I think perhaps my previous preparation made the difference.

So this is what I did. 2 days prior to the infusion , I drank lots and lots of water and took one Tylenol every 6 hours. On the day of the infusion, I drank lots of water and one hour prior to the infusion I took 2 Tylenol and one Benedryl. I am continuing to drink lots of water today.

I discovered that Reclast depletes calcium and its extremely important to supplement with daily Calcium 1500 mg and Vitamin E up to 3000 mg a day. I also found that in order for calcium to be absorbed into the body it needs to be divided up during the day , not taken just once.

I am hoping that there will be no further negative reaction in the days to come. Hope this story helps a bit!

[Parscore in reply to kmksally]

Thank you very much for the input.