Can we eradicate pca in prostate gland using HIFU(high intensity focal ultrasound) to lower tumor burden?

[Nirman]

Hello Can we eradicate pca in prostate gland using HIFU(high intensity focal ultrasound) to lower tumor burden? I mean already spreaded to bones but this treatment have very very less side effects unlike radiation and chemo treatment no blood or surgery. Anyone have researched in it or have any idea please share your knowledge.

[BrazilianRO]

Hi there!

HIFU is a big fallacy in uro oncology IMHO... it doesn't really work and it is very toxic. So toxic that they abandoned treating the whole gland and adopted partial gland treatment which is still contoversy for a primary prostate cancer treatment, bc it tends to be multicentric...

If you have metastasis to the bone but in low volume, a english study called STAMPEDE showed us that Low dose Radiotherapy to the prostate actually increased you overall survival and the treatment was very well tolerated .

[Nirman in reply to BrazilianRO]

Okay thank you

[Hidden in reply to BrazilianRO]

What is toxic about HIFU, as compared to less precise radiation? Modern HIFU apparatus provides very precise real-time position and even temperature f eedback. Radiation is a blunt instrument.

[Tall_Allen]

Unless there are less than 4 metastases, there is no benefit to treating the prostate, other than to prophylactically prevent urinary problems.

prostatecancer.news/2018/09...

If you are just thinking about it to prevent future urinary problems, whole gland TULSA-PRO can accomplish it as well as whole gland radiation:

[Nirman in reply to Tall_Allen]

Allen actually prostate tumor is creating problems for kidney and urinery obstruction

[Hidden]

I am 4 months shy of 5 years post full gland HIFU surgery. I experienced zero quality of life consequences. Urge incontinence lasted 2 days after catheter removal. 2 low dose sildenafil and I am good to go. My PSA is at 1.4 and very slowly growing and something that requires monitoring. I would categorize this as "so far so good". There's a lot of nay-saying on this site concerning HIFU. Take it with a g rain of salt. BTW, don't opt for focal or partial HIFU ablation -- treat the whole gland. You may need TURP surgery prior to that. My cancer had NOT spread prior to the surgery. I still think that reducing the tumor burden is a good thing. Conventional wisdom opposes that opinion. It should be your choice.

[Bigm789 in reply to Hidden]

Did you have a PSMA scan prior to treatment , what was the location, and staging of the biopsies in the gland , and have you experienced anejaculation and no seminal volume since procedure

[Nirman]

Thank you

[dadzone43]

look at the "SEARCH" box in the upper right hand part of your monitor There is LOTS about HIFU there. It does nothing for PCa _outside_ of the gland of course. Longterm outcomes stacking HIFU against RT or RP are not as good. Check it out and inform yourself.