Taxotere response: Have finished... - Advanced Prostate...

Advanced Prostate Cancer

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Taxotere response

Newyork6264 profile image
6 Replies

Have finished 6 sessions of Taxtere and response has been as follows:

Starting PSA: 30

then as follows after each session: 20, 12, 10, 7.9, 5.87, 5.75. Alt Phos has gone from 390 to 63.

Is this leveling off normal? Does it mean that Taxotere has stopped working? Any input is appreciated.

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Newyork6264
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6 Replies

Might want to give it time. It took a year after finishing Taxotere for my PSA to bottom out (0.1).

Shooter1 profile image
Shooter1

What else are you doing/taking for your Pca. I am on xtandi after taxotere which dropped mine for another year+ to get to 0.12 average test.

Newyork6264 profile image
Newyork6264 in reply to Shooter1

Was on Zytiga and it brought my PSA down from 250 to 7 but then stopped working. Only on Lupron and Doctaxel now.

This looks like a good response. From what I know: taking Docetaxel when castrate resistant, you would continue until it either stops working or the side effects become intolerable. I think you'd want to look at radiographic progression in order to make that decision.

I noticed in another post that were said you were BRCA2 positive. That should make it possible for you take a PARP inhibitor for your next treatment.

These are things you can discuss with your doctor. Wishing you the best.

Newyork6264 profile image
Newyork6264 in reply to

Doc did say a Parb inhibitor is next. So far side effects have been tolerable. Doc is saying maybe 10 treatments,

Shooter1 profile image
Shooter1 in reply to Newyork6264

I went 9 cycles with xtani added after 4. Permanent neuropathy in hands and feet. Was aiming for 10 but side effects added up too much to continue.

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