Started ARV 110 last Monday

[Bob10]

Just wanted to inform my brothers I started a new trial at Yale University I had one of the mutations that seem to respond well, so far first week of trial is going well going Monday for blood draws praying 🙏 for so good Respond

[Longterm101]

Hoping you have a long successful remission

[Bob10 in reply to Longterm101]

Thanks my brother

[Hidden]

I think this can be great news .....Well ,Yale it is then ! You could be in many worse places ......Trials are good....just Get past the treatments and keep loving the beautiful family . Great reasons to live .. Im pulling for you to knock the pc back to the dark ages . Where it belongs .Good luck Bob10 .. hang in there ...

[Bob10 in reply to Hidden]

Thanks so much whimpy my Oncologist is at Dana Farber . I’ll keep everybody posted !I’m running out of options looking at Car T therapy at Dana after the New Year’s if this doesn’t work

[Magnus1964]

Good luck, keep us informed of progress. Warrior on.

[Bob10 in reply to Magnus1964]

Thanks Magnus I will

[George71]

Great news Bob -- keep us posted -- ARV 110 -- can be a first in class game changer.

[Bob10 in reply to George71]

George I’ll be in touch thanks

[j-o-h-n]

Go get em Robert.......... never give in........

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 12/06/2020 11:29 PM EST

[baltha]

What mutation do you have? Wishing you all the best.

[Bob10 in reply to baltha]

AR-T878A It occurs in about 10% of prostate cancer I did it at foundation one it was determined that Zytiga and other similar drugs wouldn’t work for long

[baltha in reply to Bob10]

Thanks. I wanted to confirm my expectation. My MO had recommended this ARV-110 Trial but I learned from the Arvinas press release about the two predictive mutations of the two successful patients in the pre-clinical trials. I don't have either (based on my Foundation One profile) so I decided not to take the trial. Best of Luck to you.P.S. Did you do the research about the mutations in the clinical trial or was it your oncologist?

[Bob10 in reply to baltha]

I would say both of us

[monte1111]

Also wishing you the best. I don't seem to have any mutations. Maybe if I go hang around a herd of cows I might get lucky. Or I could visit the Bronx. Go Jets!

[Bob10]

AR-T878A baltha I did the Foundation one It was one of the genomic findings sorry AR

[baltha]

And which company tested for the AR line mutations such as you have? I did the Foundation Medicine Liquid CX and those line mutations are not listed in the 311 genes tested. Any info much appreciated Bob.

[Bob10 in reply to baltha]

Foundation one

[NWLiving]

Just wondering how you are doing....

[Bob10 in reply to NWLiving]

Me