In my 17 years of prostate cancer, my third recurrence started in May 2019 with a PSA of 0.3. In prior PSA testing, I never experienced a PSA decrease unless hormones (Lupron) or radiation was involved... until now. In 2019 I started with high dose vitamin D, intermittent fasting, lost 15 pounds, eliminated dairy, and started the COC protocol (October). After a surge in liver markers ALT and AST, cut back on the Atorvastatin dose to 40 mg in December. Many supplements including vitamin C every three hours, green tea extract, artemisinin, flax seed oil, low dose aspirin.
Now, PSA went down to 0.4 after peaking at 0.5 and liver markers are in normal range. Success. PSA can stay at this low level indefinitely, though NED would be nice. I'd like to get off the Doxycycline (part of COC), but have not decided when.
The graph shows how fast PSA rose (geometric mean) during the three recurrences 2008, 2012, 2019. Doubling rate is 22 months now. Initial diagnosis was in 2002 with radioactive seeds implanted in 2003.
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Cicero2K
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I like the changes that you have made and losing the weight . Let’s pray this third time that you can push it down again . I call you a marathon man . You inspire me to push on also . Thank you 🙏
Congratulations! And it is great having the opportunity to talk to another member who has tried the COC Protocol. Did you use mebendazole or fenbendazole? At what dosage?
As I mentioned in my post, I started to develop intolerance to doxycycline. It also appears that it contributed to weight gain. I believe some members on this forum use minocycline which may be more tolerable.
Mebendazole dose is 111 milligrams, daily. I was able to get my liver markers in line by cutting the Atorvastatin and this was also the experience with other COC patients. NED is no evidence of disease, jargon. There's many off-label / supplement cancer fighters on several Facebook groups.
I took the probiotic VSL-3 to help ameliorate the effect of doxycycline on the gut. The gut is still not working as well as pre doxycycline. According to a paper from Isreal it takes a long time for the gut to stabilize/recover even with probiotics (actually longer with probiotics). There is no probiotic that has a composition that matches the optimum gut flora, which appear to be very difficult to cultivate. Fecal transplants from healthy donors would be best, but not practical of course. Cheers,
Caution about the "Doxy 30-days on & 30-days off!" It may not be accurate for everyone as they issue you own adjuntive therapy metabolic treatment plan. When you sign up with Care Oncology you first provide your most recent blood labs, scan reports, etc. to the Care Oncology MD. You are then schedule with a Zoom conference with the MD (mine was one hour long) to get aquainted, ask questions, provide a better understanding of your medical situation and to discuss your "specific" four COC medications schedule with your MD oncologist. They will also interact with your current MD team if you wish. You may be monitored by providing your blood labs monthly for the first three month on the COC protocol cocktails. You meet again with your Care Oncology MD every three months. Also, you have access to oncology experienced nurse support contact anytime. I got a reply the same day to ask a question. The reason the COC protocol doses might change is is two-fold. First, everyone's PCa involvement and existing/prior treatment(s) when you start up with Care Oncology will be different. Therefore, the slight variations. Second, Care Oncology processing and databasing of their patients status/results/outcomes with the types of cancers they have treated/been involved with is documented. Thus, what has works best (COC protocol) for say breast cancer vs. advanced prostate cancer might vary. My script was Doxy 100mg daily with breakfast or lunch for 90-days. No problems with the gut, but I had been taking daily probiotics the past year.
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