There were 4134 confirmed prostate cancer cases out of the 49,472 men in the PLCO cohort between 1998 and 2013 during the average of 11.2 follow-up years. As descriptive analysis, after classifying participants into quartiles of total dairy product consumption, the fourth quartile (>194.7 g/1000 kcal) had the most prostate cancer cases, although only slightly (Table 1). Those in the highest quartile of total dairy intake tended to be slightly older, to be non-Hispanic white, to have a personal history of diabetes, to be never or former alcohol drinkers, and to be never smokers, when compared with those in the lowest quartile. The maximum PSA levels tended to be higher in the higher quartiles; however, there was no clear pattern in the frequency of prostate cancer screenings based on PSA and DRE. Similarly, across quartiles of total dairy consumption, no clear pattern was observed in educational attainment, family history of cancer, BMI, ibuprofen use, and physical activity engagement. Those at higher quartiles tended to report lower total energy intake than those in lower quartiles.
Total dairy products had no statistically significant association with prostate cancer risk (HR = 1.05, 95% CI = 0.96–1.15 for highest quartile compared with lowest quartile, P-trend = 0.48) (Table 2). Similarly, there were no associations with low-fat dairy products (HR = 1.07, 95% CI = 0.98–1.17, P-trend = 0.34) or regular-fat dairy products (HR = 1.05, 95% CI = 0.96–1.15, P-trend = 0.90). When we grouped dairy products by fermentation methods, neither fermented dairy products (HR = 1.01, 95% CI = 0.93–1.10, P-trend = 0.92) nor non-fermented dairy products (HR = 1.07, 95% CI = 0.98–1.17, P-trend = 0.15) had a statistically significant association with prostate cancer risk. Similarly, milk intake variables, as total or separately by fat content, were not associated with a risk of prostate cancer (Table 3). The HR (95% CI) for total milk was 1.06 (0.97–1.15) comparing the highest quartile with the lowest with a P-trend of 0.39. By individual milk intake, the HR (95% CI) for comparing the higher than median intake and no intake ranged from 1.00 (0.92–1.09) for skim/nonfat/0.5%-fat milk to 1.06 (0.98–1.15) for 2%-fat milk.
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I always say "do not trust fake news and fake research" The whole world knew that dairy products do not cause prostate cancer but the fake research maligned milk and milk products.
If milk and yogurt caused prostate cancer, the highest rates of PCa would be in China, India and other Asian nations. But its the reverse...the rates of PCa is lowest in milk drinking Asian nations and highest in red meat eating nations.
Finally , the truth comes out as it came out with cigarrette industry....people are smart ..they get it eventually.
Milk and yogurt keeps your bones strong...every mother knows that.
Obviously controversial, but I've read so many studies that link milk and its protein casein to progressive PCa growth through increased signaling in the mTORC pathway (see diagram in the link).
For this reason, I mostly dropped natural milk for yogurt and powdered milk which have less casein.
”Persistent consumption of cow's milk proteins in humans provide highly insulinotropic branched-chain amino acids (BCAAs) provided by milk's fast hydrolysable whey proteins, which elevate postprandial plasma insulin levels, and increase hepatic IGF-1 plasma concentrations by casein-derived amino acids. BCAAs, insulin and IGF-1 are pivotal activating signals of mTORC1. Increased cow's milk protein-mediated mTORC1 signaling along with constant exposure to commercial cow's milk estrogens derived from pregnant cows may explain the observed association between high dairy consumption and increased risk of PCa in Westernized societies.“
Note specifically the exceptions: "except for regular-fat dairy product intake with late-stage prostate cancer risk (HR = 1.37, 95% CI = 1.04–1.82 comparing the highest with lowest quartile) and 2%-fat milk intake with advanced prostate cancer risk (HR = 1.14, 95% CI = 1.02–1.28 comparing the higher than median intake with no intake group)"
Looks like high intake of dairy fat is still a problem.
As to your question if it applies to post RP, I would expect so if you have dormant, undetectable cancer cells lurking in your body. Also, if you have a genetic mutation that contributed in part to your prostate cancer, removing the prostate won't prevent those genes from contributing to other cancers.
We should not take one part of study and make general statement. Biggest proof is that communities where everyone drinks milk and eats yogurt every day do not have higher rates of prostate cancer.
Only way Milk products can cause harm is by excessive eating of these as these products are rich in calories, protein ,fat and calcium...it can lead to Obseity and its medical consequences. Direct adverse effect on PCa does not happen. Again, moderation is the key.
Substitute Almond milk if it concerns you about dairy ..quite good actually, substitute yogurt for ice cream?..enjoy what you want, not going to change anything at this point.
Early-life milk intake may have a role in the development of prostate cancer, particularly around puberty when the prostate grows and matures. Why would stopping drinking milk in late-life make a difference if you already have cancer?
From a Scandinavian study: ncbi.nlm.nih.gov/pmc/articl...Frequent milk intake at ages 14–19 years was associated with a 3-fold elevation in risk for advanced prostate cancer. These findings highlight the potential role of early-life diet in prostate cancer risk and are consistent with migrant studies showing that it takes at least 1 generation for migrants to incur the prostate cancer risk of the host country.
I can advise that although there is too much fat in milk, I have throughout my adult life drank skim milk to the tune of a liter a day. There was some thought that the estrogen contained in milk had a positive impact. I know that when I do not get my glass a day, I notice a negative impact on my general well being. Perhaps I was weaned too early, hmmm but it is the only factor that I have come up with that explains why I have lasted this long, as I have done nothing great in terms of making radical changes to my lifestyle, but do try to eat healthy, cut down on booze, never smoked, was a marathon runner for many years, so the early physical activity has played a roll in keeping me alive now, when the wheels are falling off throughout my body.
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