Can Nubeqa be utilized after Erleada or Xtandi no longer work?
Nubeqa after Erleada?: Can Nubeqa be... - Advanced Prostate...
Nubeqa after Erleada?
![ncisc001 profile image](https://images.hu-production.be/avatars/e37bf2242cb7498094878528e06411a0_small@2x_100x100.jpg)
Written by
![ncisc001 profile image](https://images.hu-production.be/avatars/e37bf2242cb7498094878528e06411a0_small@2x_100x100.jpg)
ncisc001
To view profiles and participate in discussions please or .
Read more about...
3 Replies
•
If you are non-metastatic, you can try it. There is no data yet on cross-resistance.
Please TA, help us dummies understand the molecular process of cross resistance, especially as it might apply here.
It means that all the ways that the androgen receptor mutates to become resistant to one hormonal therapy also creates resistance to other hormonal therapies. Those ways include AR amplification, AR translocation to the nucleus, internal androgen production, mutant ARs that do not need to dimerize and do need androgens at all, and mutant ARs that are activated by other ligands.
Not what you're looking for?
You may also like...
Stopping Erleada Starting Nubeqa
I have been on Erleada since mid-January. It has knocked my PSA down from 13.4 to 1.5 in 5 months....
Erleada
I have been on everything. Have at PC for 17 years and am now 86. Psa is
up to 84 and would still...
What's different between Xtandi vs NUBEQA® (darolutamide) vs ERLEADA® (apalutamide)
Hello Everyone,
zytiga didn’t work so move to xtandi
After two months, Xtandi did not work, and...
Nubeqa headaches?
Hi all,
My dad started Nubeqa on May 11th as part of his triplet therapy. He noticed that he’s...
Erleada failing?
Hi all!
My father has been battling PC since April 2016. To make a long story short, his...