New oral GnRH antagonist shows 97% response rate in Phase III trial

[curious-mind1]

It looks like there is a tablet version of GnRH antagonists soon to be approved. This is an alternative to Lupron-class drugs, in tablet form. The trial has show it supresses T levels quicker than Lupron, but the side effect profile is similar:

investors.myovant.com/news-...

Best,

Arthur

[IrishDude]

I think this is the product the the survey some of us took recently was meant to provide research for.

[Hidden]

Another drug? Good news! Too bad it has the similar side effect profile though .😫

[mcp1941]

Just what the drug companies love. Another pill to charge thousands of dollars when the injection is no cost to the patient.

Mike P.

[IrishDude in reply to mcp1941]

Actually when I took the survey they definitely asked leading questions about the cost vs convenience issues. I pretty much told them that a once a six month visit for a shot I don't pay for is hard to beat. Their product supposedly wears off much faster, so that might be a plus in some cases.

[GeorgesCalvez]

It is a GnRH antagonist which puts it in the same class of drugs as abarelix, which was withdrawn due to its histamine releasing properties, and degarelix which is still on the market as Firmagon.

It has similar properties to these drugs causing a rapid fall in testosterone to subcastrate levels in a few days.

My guess is that it will be used to induce sub castration levels of testosterone before switching to leuprolide in most cases which will be better for most patients as the double shot of degarelix aka Firmagon is pretty painful.

[j-o-h-n]

Another Pill? (running out of space in my pill box).

So this guy thinks he gets high from taking homeopathic pills.

That’s an oxy, moron.

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 11/20/2019 7:49 PM EST

[ellie2211]

Why would they give this instead of lupron?