dropped bicalutamide added Zytiga

[pj1121]

lupron and bicalutamide for one month. PSA dropped 300/33 testosterone dropped 650/20. Then another month of treatment.(no PSA yet )

Five days ago stopped bicalutamide and added Zytiga. Sexual interest/function seems to have returned. Is this coincidence or an issue with meds?? Good news bad news?

Thoughts appreciated

Thanks

Pj

[dhccpa]

I suspect as long as you're on Lupron, your libido as you knew it will be history. But you may be the exception!

[pj1121 in reply to dhccpa]

My concern is after stopping the bicalutamide which is an androgen receptor antagonist the different action of zytiga does not work as well for me as the bicalutamide did when I had no libido.

[j-o-h-n in reply to pj1121]

Great Question..................... Greater Answer: LOWBIDO.

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 09/03/2023 6:34 PM DST

[Gearhead]

Yours is an unusual situation. Hope your libido maintains. Please keep us informed.

[Mgtd]

Might get a testosterone test to see if Lupron is working.

[Echotango51]

That would be good news, I have never taken Zytiga, been on lupron , xtandi now for 14 months PSA 0.06. Been on lupron continuously since 2016, testosterone 3 no sex drive at all good luck.